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Table 1 Participants characteristics at hospital admission

From: Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study

  Exposed to historical lineages Exposed to VOC Alpha P-value
N = 650 N = 650
Age (years), median (range) 70 (27–100) 70 (25–101)  
Gender—n (%)    
 Male 399 (61.4) 399 (61.4)  
 Female 251 (38.6) 251 (38.6)  
Body Mass Index    0.20
 N 571 553  
 Median (range) 26.8 (13.5–67.2) 27.4 (3.3–76)  
Smoker—n (%) 169 (26.0) 136 (20.9) 0.04
Location of initial care—n (%)    0.12
 Conventional hospitalization 560 (86.2) 539 (82.9)  
 ICU 90 (13.8) 109 (16.7)  
Comorbidities, n (%) 586 (90.1) 553 (85.0) 0.004
 Cardiovascular disease 410 (62.9) 401 (61.6) 0.57
 Chronic lung disease 102 (15.6) 74 (11.3) 0.02
 Asthma 35 (5.3) 33 (5.0) 1.00
 Chronic kidney disease 87 (13.3) 70 (10.7) 0.11
 Chronic liver disease 21 (3.2) 12 (1.8) 0.11
 Chronic neurological disease 115 (17.6) 88 (13.5) 0.03
 Active cancer 80 (12.3) 53 (8.1) 0.01
 Solid organ transplant 31 (4.7) 13 (2.0)  < 0.001
 Autoimmune disease 27 (4.1) 20 (3.0) 0.15
 HIV Infection 10 (1.5) 0 (0)  
 Obesity 164 (25.2) 176 (27.0) 0.54
 Diabetes 197 (30.3) 182 (27.9) 0.29