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Table 1 Participants characteristics at hospital admission

From: Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study

 

Exposed to historical lineages

Exposed to VOC Alpha

P-value

N = 650

N = 650

Age (years), median (range)

70 (27–100)

70 (25–101)

 

Gender—n (%)

   

 Male

399 (61.4)

399 (61.4)

 

 Female

251 (38.6)

251 (38.6)

 

Body Mass Index

  

0.20

 N

571

553

 

 Median (range)

26.8 (13.5–67.2)

27.4 (3.3–76)

 

Smoker—n (%)

169 (26.0)

136 (20.9)

0.04

Location of initial care—n (%)

  

0.12

 Conventional hospitalization

560 (86.2)

539 (82.9)

 

 ICU

90 (13.8)

109 (16.7)

 

Comorbidities, n (%)

586 (90.1)

553 (85.0)

0.004

 Cardiovascular disease

410 (62.9)

401 (61.6)

0.57

 Chronic lung disease

102 (15.6)

74 (11.3)

0.02

 Asthma

35 (5.3)

33 (5.0)

1.00

 Chronic kidney disease

87 (13.3)

70 (10.7)

0.11

 Chronic liver disease

21 (3.2)

12 (1.8)

0.11

 Chronic neurological disease

115 (17.6)

88 (13.5)

0.03

 Active cancer

80 (12.3)

53 (8.1)

0.01

 Solid organ transplant

31 (4.7)

13 (2.0)

 < 0.001

 Autoimmune disease

27 (4.1)

20 (3.0)

0.15

 HIV Infection

10 (1.5)

0 (0)

 

 Obesity

164 (25.2)

176 (27.0)

0.54

 Diabetes

197 (30.3)

182 (27.9)

0.29