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Table 2 Characteristics of all study participants at the Emergency Department

From: A retrospective cohort study of the effect of SARS-CoV-2 point of care rapid RT-PCR at the Emergency Department on targeted admission

 

Period 1 (N = 781)

Period 2 (N = 988)

Period 3 (N = 1171)

P value

Total (N = 2940)

n = 

% (95% CI)

n = 

% (95% CI)

n = 

% (95% CI)

 

n = 

% (95% CI)

Demographic data of study participants

 Age [mean (± SD)]

61 (± 22)

 

66 (± 18)

 

61 (± 20)

 

P = 0.04

61 (± 21)

 

 Female sex

417

46.6 (43.1–50.1)

489

50.5 (47.4–53.6)

591

49.5 (46.6–52.3)

P = 0.27

1497

50.9 (49.1–52.7)

SARS-CoV-2 test results

 Positive test at the ED

70

9.0 (7.2–11.2)

135

13.7 (11.7–15.9)

203

17.3 (15.3–19.6)

 

408

13.9 (12.7–15.2)

 Negative test at the ED

374

47.9 (44.4–51.4)

515

52.1 (49.0–55.2)

569

48.6 (45.7–51.5)

 

1458

49.6 (47.8–51.4)

 Positive test before admission

92

11.8 (9.7–14.2)

193

19.5 (17.2–22.1)

283

24.2 (21.8–26.7)

 

568

19.3 (17.9–20.8)

 Not tested

245

31.4 (28.2–34.7)

145

14.7 (12.6–17.0)

116

9.9 (8.3–11.8)

 

506

17.2 (15.9–18.6)

ICD-10 diagnosis at discharge from ED

 Covid-19

53

6.8 (5.2–8.85)

146

14.8 (12.7–17.1)

229

19.6 (17.4–21.9)

 

428

14.6 (13.3–15.9)

 Respiratory symptoms

109

14.0 (11.7–16.6)

163

16.5 (14.3–18.9)

143

12.2 (10.5–14.2)

 

415

14.1 (12.9–15.4)

 Other infection

103

13.3 (11.0–15.7)

107

10.8 (9.0–12. 9)

106

9.1 (7.5–10.8)

 

316

10.7 (9.7–11.9)

 Chest pain or heart disease

95

12.2 (10.1–14.6)

95

9.6 (7.9–11.6)

107

9.1 (7.6–10.9)

 

297

10.1 (9.1–11.2)

 Abdominal pain or GI symptoms

93

11.9 (9.8–14.4)

78

7.9 (6.4–9.7)

102

8.7 (7.2–10.5)

 

273

9.3 (8.3–10.4)

 Other internal medicine

58

7.4 (5.8–9.5)

54

5.5 (4.2–7.1)

78

6.77 (5.4–8.2)

 

190

6.5 (5.6–7.4)

 Neurological deficit or symptoms

53

6.4 (5.2–8.8)

48

4.9 (3.7–6.4)

59

5.0 (3.9–6.4)

 

160

5.4 (4.7–6.3)

 Other respiratory tract infection

35

4.5 (3.2–6.2)

30

3.0 (2.1–4.3)

41

3.5 (2.6–4.7)

 

106

3.6 (3.0–4.3)

 Trauma

25

3.2 (2.2–4.7)

34

3.4 (2.5–4.8)

29

2.5 (1.7–3.5)

 

88

3.0 (2.4–3.7)

 Other orthopedic diagnose

20

2.6 (1.7–3.9)

16

1.6 (1.0–2.6)

34

2.9 (2.1–4.0)

 

70

2.4 (1.9–3.0)

 Other surgery or urology

20

2.6 (1.7–3.9)

10

1.0 (1.9–0.6)

17

1.5 (0.9–2.3)

 

47

1.6 (1.2–2.1)

 No diagnosis

91

11.7 (9.6–14.1)

173

17.5 (15.3–20.0)

180

15.4 (13.4–17.6)

 

444

15.1 (13.9–16.4)

 Other

26

3.3 (2.3–4.8)

34

3.4 (2.5–4.8)

46

3.9 (3.0–5.2)

 

106

3.6 (3.0–4.3)

Discharge from ED

 Discharge to home from ED, total

395

50.6 (47.1–54.1)

478

48.4 (45.3–51.5)

580

49.5 (46.7–52.4)

 

1453

49.4 (47.6–51.2)

  Positive test at the ED

20

2.6 (1.7–3.9)

50

5.1 (3.9–6.6)

81

6.9 (5.6–8.5)

 

151

5.1 (4.4–6.0)

  Negative test at the ED

119

15.2 (12.9–17.9)

207

21.0 (18.5–23.6)

268

22.9 (20.6–25.4)

 

594

20.2 (18.8–21.7)

  Positive test before admission

51

6.5 (5.0–8.5)

104

10.5 (8.8–12.6)

136

11.6 (9.9–13.6)

 

291

9.9 (8.9–11.0)

  Not tested

205

26.2 (23.3–29.4)

117

11.8 (10.0–14.0)

95

8.1 (6.7–9.8)

 

417

14.2 (13.0–15.5)

 Hospital admissions, total

386

49.4 (45.9–52.9)

510

51.6 (48.5–54.7)

591

50.5 (47.6–53.3)

 

1487

50.6 (48.8–52.4)

  Positive test at the ED

50

6.4 (4.9–8.3)

85

8.6 (7.0–10.5)

122

10.4 (8.8–12.3)

 

257

8.7 (7.8–9.8)

  Negative test at the ED

255

32.7 (29.5–36.0)

308

31.2 (28.4–34.1)

301

25.7 (23.3–28.3)

 

864

29.4 (27.8–31.1)

  Positive test before admission

41

5.2 (3.9–7.0)

89

9.0 (7.4–11.0)

147

12.6 (10.8–14.6)

 

277

9.4 (8.4–10.5)

  Not tested

40

5.1 (3.8–6.9)

28

3.6 (2.5–5.1)

21

1.8 (1.2–2.7)

 

89

3.0 (2.5–3.7)

ICD-10 diagnosis, death at ED or hospital ward

 Covid-19

13

1.7 (1.0–2.8)

29

2.9 (2.1–4.2)

58

5.0 (3.9–6.3)

 

100

3.4 (2.8–4.1)

 Other infection

3

0.4 (0.1–1.1)

11

1.1 (0.6–2.0)

11

0.9 (0.5–1.7)

 

25

0.9 (0.6–1.3)

 Cardiovascular disease

15

1.9 (1.2–3.1)

6

0.6 (0.3–1.3)

17

1.5 (0.9–2.3)

 

38

1.3 (0.9–1.8)

 Neurological disease

7

0.9 (0.4–1.8)

2

0.2 (0.04–0.7)

9

0.8 (0.4–1.5)

 

18

0.6 (0.4–1.0)

 Malignancy

3

0.4 (0.1–1.1)

5

0.5 (0.2–1.2)

3

0.3 (0.1–0.8)

 

11

0.4 (0.2–0.7)

 Other

3

0.4 (0.1–1.1)

8

0.8 (0.4–1.6)

1

0.1 (0.004–0.5)

 

12

0.4 (0.2–0.7)

 Hospital deaths, total

44

5.6 (4.2–7.5)

61

6.2 (4.8–7.9)

99

8.5 (7.0–10.2)

 

204

6.9 (6.1–7.9)

  1. Demographic data, SARS-CoV-2 test results and discharge diagnoses of all included patients, in all three study periods. The fraction of participants with positive SARS-CoV-2 tests taken at the Emergency department (ED) or before admission to the ED increased during the study period, as did Covid-19 diagnosis at discharge. ICD-10 diagnoses were grouped into compound variables (described in detail in Additional file 1). Total number of participants in each period (N =) and in each subgroup (n =) are presented with percentage as fraction of total and 95% confidence interval (CI) to enable comparisons between the periods, or mean value with standard deviation (SD), as indicated. P-values calculated by One-Way-ANOVA with Tukey’s multiple comparison tests