Table 2 Univariate and multivariate analysis of esophageal perforation in 521 patients with deep neck infection
From: Factors affecting perforation of the esophagus in patients with deep neck infection
Variable | Esophageal perforation | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|---|
Yes | No | OR | 95% CI | p value | OR | 95% CI | p value | |
Gender | 32 | 489 | 0.272 | – | – | – | ||
Male | 18 | 322 | 1.000 | |||||
Female | 14 | 167 | 1.499 | 0.727–3.090 | ||||
Age, years | 0.413 | – | – | – | ||||
≤ 50 | 13 | 235 | 1.000 | |||||
> 50 | 19 | 254 | 1.353 | 0.653–2.801 | ||||
Chief complaint days (SD) | 3.81 ± 2.44 | 4.90 ± 4.31 | 0.909 | 0.796–1.037 | 0.102 | – | – | – |
CRP, mg/L (SD) | 187.56 ± 107.89 | 145.01 ± 106.61 | 1.003 | 1.000–1.006 | 0.031* | – | – | – |
Blood sugar, mg/dL (SD) | 156.15 ± 88.16 | 144.38 ± 72.44 | 1.001 | 0.997–1.006 | 0.401 | – | – | – |
Diabetes mellitus | 0.156 | – | – | – | ||||
No | 15 | 292 | 1.000 | |||||
Yes | 17 | 197 | 1.679 | 0.819–3.442 | ||||
Multiple spaces, ≥ 3 | < 0.001* | – | – | – | ||||
No | 12 | 337 | 1.000 | |||||
Yes | 20 | 152 | 3.695 | 1.761–7.751 | ||||
Retropharyngeal space | < 0.001* | 0.006* | ||||||
No | 6 | 341 | 1.000 | |||||
Yes | 26 | 148 | 9.984 | 4.025–24.76 | 5.449 | 1.603–18.51 | ||
Parapharyngeal space | 0.262 | – | – | – | ||||
No | 16 | 195 | 1.000 | |||||
Yes | 16 | 294 | 1.507 | 0.736–3.085 | ||||
Submandibular space | 0.103 | – | – | – | ||||
No | 21 | 249 | 1.000 | |||||
Yes | 11 | 240 | 1.841 | 0.868–3.898 | ||||
Masticator space | 0.890 | – | – | – | ||||
No | 24 | 372 | 1.000 | |||||
Yes | 8 | 117 | 1.059 | 0.463–2.422 | ||||
Anterior cervical space | 0.349 | – | – | – | ||||
No | 28 | 452 | 1.000 | |||||
Yes | 4 | 37 | 1.745 | 0.580–5.242 | ||||
Parotid space | 0.774 | – | – | – | ||||
No | 26 | 407 | 1.000 | |||||
Yes | 6 | 82 | 1.145 | 0.457–2.870 | ||||
Perivertebral space | 0.823 | – | – | – | ||||
No | 31 | 470 | 1.000 | |||||
Yes | 1 | 19 | 1.253 | 0.162–9.671 | ||||
Carotid space | 0.078 | – | – | – | ||||
No | 27 | 458 | 1.000 | |||||
Yes | 5 | 31 | 2.736 | 0.985–7.596 | ||||
Visceral space | 0.202 | – | – | – | ||||
No | 28 | 459 | 1.000 | |||||
Yes | 4 | 30 | 2.185 | 0.719–6.638 | ||||
Posterior cervical space | 0.635 | – | – | – | ||||
No | 31 | 480 | 1.000 | |||||
Yes | 1 | 9 | 1.720 | 0.211–14.07 | ||||
Mediastinitis | < 0.001* | < 0.001* | ||||||
No | 5 | 471 | 1.000 | |||||
Yes | 27 | 18 | 141.3 | 48.75–409.4 | 218.8 | 55.98–855.3 | ||