Table 3 Unadjusted and adjusted Cox regression analysis of factors associated with survival stratified by HBV coinfection status
Covariates | Category | CHRa (95% CIs) | p-valueb | AHRc (95% CIs) | p-valueb |
|---|---|---|---|---|---|
HBsAg results (ref. positive) | Positive | 1.65 (1.08–2.52) | 0.019 | 0.84 (0.52–1.36) | 0.486 |
Sex (ref. Female) | Male | 1.87 (1.53–2.289) | < 0.001 | 1.39 (1.11–1.76) | 0.005 |
Age (ref. 15–24) | 25–34 | 0.84 (0.49–1.42) | 0.512 | 1.00 (0.54–1.83) | 0.991 |
35–44 | 1.13 (0.69–1.83) | 0.631 | 1.12 (0.64–1.97) | 0.695 | |
45–54 | 1.22 (0.75–2.00) | 0.413 | 1.13 (0.64–2.00) | 0.671 | |
55–64 | 1.90 (1.14–3.16) | 0.014 | 1.66 (0.91–3.01) | 0.096 | |
65+ | 5.07 (2.93–8.77) | < 0.001 | 3.41 (1.80–6.49) | < 0.001 | |
Province (ref. Kigali City) | East | 0.58 (0.18–1.83) | 0.352 | 0.53 (0.13–2.15) | 0.373 |
North | 2.07 (1.57–2.72) | < 0.001 | 2.03 (1.49–2.78) | < 0.001 | |
South | 1.47 (1.06–2.03) | 0.019 | 1.57 (1.10–2.24) | 0.013 | |
West | 1.64 (1.26–2.14) | < 0.001 | 1.55 (1.14–2.09) | 0.005 | |
Current or former drinker (ref. No) | Yes | 3.92 (4.01–6.03) | < 0.001 | 4.20 (3.32–5.31) | < 0.001 |
WHO stages (ref. 1&2nd stage) | 3&4 stage | 1.85 (1.47–2.32) | < 0.001 | 2.15 (1.68–2.75) | < 0.001 |
Time since ART initiation (ref. < 7 years) | ≥ 7 years | 0.66 (0.52–0.84) | 0.001 | 0.53 (0.41–0.70) | < 0.001 |
Ever smoked (ref. No) | Yes | 2.49 (1.62–3.83) | < 0.001 | 0.92 (0.57–1.49) | 0.736 |
Ever had tuberculosis (ref. No) | Yes | 1.92 (1.32–2.79) | 0.001 | 1.33 (0.86–2.06) | 0.200 |
TDF based regimen (ref. No) | Yes | 0.95 (0.76–1.20) | 0.676 |