Table 2 Mortality rates per 100,000 person months
Covariates | Category | Overall frequency (%) (n = 18,459) | Number of deaths, n = 394 (2.1%) | Person-months of follow-up = 862,152 | Mortality rates per 100,000 person-months (95% CIs) 45.7 (41.4–50.4) |
|---|---|---|---|---|---|
HBsAg | Negative | 17,826 (96.6) | 371 (2.1) | 832,495 | 44.5 (40.2–49.3) |
Positive | 633 (3.4) | 23 (3.6) | 29,657 | 77.5 (51.5–116.7) | |
Sex | Female | 12,009 (65.1) | 190 (1.6) | 560,010 | 33.9 (29.4–39.1) |
Male | 6424 (34.8) | 204 (3.2) | 300,907 | 67.8 (59.1–77.8) | |
Unknown | 26 (0.1) | ||||
Age | Mean (SD) | 42.3 (11.4) | |||
15–24 | 1131 (6.1) | 19 (1.7) | 52,972 | 35.9 (22.9–56.2) | |
25–34 | 3520 (19.1) | 49 (1.4) | 164,656 | 29.7 (22.5–39.4) | |
35–44 | 5962 (32.3) | 112 (1.9) | 278,602 | 40.2 (33.4–48.4) | |
45–54 | 5188 (28.1) | 107 (2.1) | 242,476 | 44.1 (36.5–53.3) | |
55–64 | 2069 (11.2) | 66 (3.2) | 96,390 | 68.4 (53.8–87.1) | |
65+ | 470 (2.5) | 39 (8.3) | 21,481 | 181.5 (132.6–248.5) | |
Unknown | 119 (0.6) | 2 (1.7) | |||
Province | City of Kigali | 6660 (36.1) | 98 (1.5) | 311,615 | 31.5 (25.8–38.3) |
East | 329 (1.8) | 3 (0.9) | 15,583 | 19.2 (6.2–59.7) | |
North | 3601 (19.5) | 104 (2.9) | 166,030 | 62.6 (51.7–75.9) | |
South | 2804 (15.2) | 59 (2.1) | 130,224 | 45.3 (35.1–58.5) | |
West | 5065 (27.4) | 130 (2.6) | 238,699 | 54.5 (44.9–64.7) | |
Current or past smokers | No | 17,953 (97.3) | 368 (2.0) | 838,705 | 43.9 (39.6–48.6) |
Yes | 428 (2.3) | 22 (5.1) | 19,869 | 110.7 (72.9–168.1) | |
Unknown | 78 (0.4) | 4 (5.1) | |||
Current or former drinker | No | 14,130 (76.5) | 155 (1.1) | 662,049 | 23.4 (20.0–27.4) |
Yes | 4243 (23.0) | 230 (5.4) | 196,209 | 117.2 (103.0–133.4) | |
Unknown | 86 (0.5) | 9 (10.5) | |||
CD4 (cells/mm3) at HBsAg testing | Median (IQR) | 345 (168–564) | |||
< 350 | 2965 (16.1) | 63 (2.1) | 138,533 | 45.5 (35.5–58.2) | |
≥ 350 | 4446 (24.1) | 94 (2.1) | 207,634 | 44.3 (37.0–55.4) | |
Unknown | 11,048 (59.9) | 237 (2.1) | |||
HIV viral load (copies/ml) | Median (IQR) | 20 (20–20) | |||
< 1000 | 12,234 (66.3) | 205 (1.7) | 573,153 | 35.8 (31.2–41.0) | |
≥ 1000 | 480 (2.6) | 13 (2.7) | 22,385 | 58.1 (33.7–100.0) | |
Unknown | 5745 (31.1) | 176 (3.1) | |||
ART adherence | Bad (< 95%) | 1067 (5.8) | 16 (1.5) | 49,867 | 32.1 (19.7–52.4) |
Good (≥ 95%) | 16,380 (88.7) | 232 (1.4) | 767,465 | 30.2 (26.6–34.4) | |
Unknown | 1012 (5.5) | 146 (14.4) | |||
WHO-HIV clinical stage | 1&2 | 13,909 (75.4) | 217 (1.6) | 651,325 | 33.3 (29.2–38.1) |
3&4 | 3900 (21.1) | 112 (2.9) | 181,345 | 61.8 (51.3–74.3) | |
Unknown | 650 (3.5) | 65 (10.0) | |||
Tuberculosis | No | 17,701 (95.9) | 364 (2.1) | 826,936 | 44.0 (39.7–48.8) |
Yes | 758 (4.1) | 30 (4.0) | 35,215 | 85.2 (59.6–121.8) | |
Diabetes | No | 17,947 (97.2) | 373 (2.1) | 838,394 | 44.5 (40.2–49.2) |
Yes | 54 (0.3) | 0 | 2542 | 0 | |
Unknown | 458 (2.5) | 21 (4.6) | |||
TDF based regimen | No | 4608 (25.0) | 99 (2.1) | 215,216 | 46.0 (37.8–56.0) |
Yes | 13,339 (72.3) | 273 (2.0) | 623,266 | 43.8 (38.9–49.3) | |
Unknown | 512 (2.8) | 22 (4.3) | |||
Time since HIV testing | < 7 years | 7227 (39.2) | 177 (2.4) | 337,736 | 52.4 (45.2–60.7) |
≥ 7 years | 8960 (48.5) | 135 (1.5) | 419,021 | 32.2 (27.2–38.1) | |
Unknown | 2272 (12.3) | 82 (3.6) | |||
Time since ART start | < 7 years | 11,846 (64.2) | 266 (2.2) | 553,332 | 48.1 (42.6–54.2) |
≥ 7 years | 6,300 (34.1) | 94 (1.5) | 294,636 | 31.9 (26.1–39.0) | |
Unknown | 313 (1.7) | 34 (10.9) |