Table 3 Univariant and multivariant COX regression model for progression from mild/moderate cases into severe case
From: Predicting progression to severe COVID-19 using the PAINT score
Variables | Univariable logistic regression | Multivariable logistic regression | ||
|---|---|---|---|---|
OR (95%) | p value | OR (95%) | p value | |
General information | ||||
 Age, > 75 years | 1.03 (1.01–1.06) | 0.01 | 3.92 (1.61–9.73) | 0.003 |
 Sex, male | 1.494 (1.02–2.184) | 0.038 | 1.67 (0.55–5.09) | 0.364 |
Comorbidities | ||||
 Pulmonary disease | 3.625 (1.092–12.032) | 0.035 | 11.20 (2.50–49.70) | 0.001 |
 Liver disease | 3.304 (1.146–9.527) | 0.027 | 1.27 (0.26–6.34) | 0.768 |
Laboratory findings | ||||
 Lymphocyte < 1 × 109/L | 0.215 (0.087–0.529) | 0.001 | 0.73 (0.19–2.81) | 0.646 |
 NLR | 1.074 (1.012–1.140) | 0.019 | 0.73 (0.19–2.81) | 0.646 |
 AST > 40 U/L | 1.008 (1.001–1.020) | 0.017 | 4.60 (1.31–16.00) | 0.018 |
 Urea (mmol/L) | 1.066 (1.020–1.115) | 0.005 | 1.92 (0.64–5.71) | 0.243 |
 PT (s) | 1.482 (1.042–2.109) | 0.029 | 1.63 (0.63–4.24) | 0.315 |
 Cr > 133 mol/L | 1.008 (1.001–1.015) | 0.017 | 2.87 (1.18–6.98) | 0.02 |
 CD4+ T cell (/μL) | 0.097 (0.995–0.999) | 0.003 | 0.5 (0.05–5.12) | 0.556 |
 CD8+ T cell (/μL) | 0.996 (0.992–0.999) | 0.008 | 1.18 (0.25–5.52) | 0.830 |
 CD3+ T cell (/μL) | 0.998 (0.997–0.999) | 0.002 | 2.32 (0.2–27.42) | 0.505 |
 CD19+ T cell (/μL) | 0.995 (0.990–0.999) | 0.031 | 1.13 (0.29–4.41) | 0.861 |
 CD16+/CD56+ NK cell (/μL) | 0.992 (0.985–0.998) | 0.012 | 3.40 (1.31–9.13) | 0.014 |
 Ig M (g/L) | 0.260 (0.072–0.941) | 0.040 | 6.31 (1.99–19.60) | 0.002 |