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Table 3 Correlates of DBS specimens genotyping failure

From: HIV-1 drug resistance genotyping success rates and correlates of Dried-blood spots and plasma specimen genotyping failure in a resource-limited setting

Factor Genotyping failure n (%) Odds ratio (95% CI) p-value Adjusted OR [aOR (95% CI)] p-value
Pre-genotyping viral load testing
 Not done 1038/1885 (55.1) 1 < 0.0001   0.001
 Done 888/1952 (45.5) 0.68 (0.6–0.77)   0.71 (0.16–0.22)  
Viral load
 1000–10,000 cps/mL 599/897 (66.8) 1 < 0.0001   < 0.0001
 > 10,000–50,000 cps/mL 185/497 (37.2) 0.29 (0.23–0.37) 0.3 (0.24–0.38)
 > 50,000–200,000 cps/mL 73/344 (21.2) 0.13 (0.11–0.18) 0.14 (0.10–0.18)
 > 200,000 cps/mL 31/214 (14.5) 0.08 (0.06–0.13) 0.07 (0.06–0.13)
Specimen source
 Research studies 48/137 (35.0) 1 < 0.0001   0.006
 Routine clinical diagnosis 1574/3279 (48.0) 1.72 (1.36–2.18) 1.4 (1.11–1.84)
  1. Each denominator represents the number of specimens of that specific category