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Table 2 Correlates of genotyping failure for all specimens analysed from 2016 to 2019

From: HIV-1 drug resistance genotyping success rates and correlates of Dried-blood spots and plasma specimen genotyping failure in a resource-limited setting

Predictor Variable Genotyping failure n/N (%) Unadjusted OR p-value Adjusted OR p-value
Specimen type
 DBS 1926/3836 (50.2) 1 < 0.0001   < 0.0001
 Plasma 422/3001 (14.1) 0.16 (0.14–0.18) 0.10 (0.08–0.14)
Pre-genotyping viral load testing
 Not done 1398/3893 (35.9) 1 0.002   0.023
 Done 950/2944 (32.3) 0.85 (0.77–0.94) 0.64 (0.13–0.56)
Viral load
 1001–10,000 cps/mL 634/1165 (54.4) 1 < 0.0001   < 0.0001
 > 10,000–50,000 cps/mL 197/755 (25.4) 0.28 (0.23–0.35) 0.3 (0.24–0.38)
 > 50,000–200,000 cps/mL 81/609 (13.3) 0.13 (0.10–0.17) 0.14 (0.11–0.19)
 > 200,000 cps/mL 38/392 (9.7) 0.09 (0.06–0.13) 0.10 (0.07–0.14)
Specimen source
 Research studies 745/3533 (21.1) 1 < 0.0001   0.005
 Routine clinical diagnosis 1603/3304 (48.5) 3.5 (3.17–3.92) 1.4 (1.10–1.75)
  1. Each denominator represents the number of specimens of that specific category