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Table 4 Hazard ratios (HR) of dying in the follow-up period of 91–365 days after first visit, their respective 95% confidence intervals (CI), and p-values for Cox proportional hazard models

From: Early mortality in a cohort of people living with HIV in Rio de Janeiro, Brazil, 2004–2015: a persisting problem

Variables

Unadjusted model

HR (95% CI)

p-value

Adjusted model

HR (95% CI)

p-value

Age

 10 year increase

1.70 (1.44–2.01)

< 0.0001

1.57 (1.25–1.97)

< 0.001

Ethnicity/skin color

 White

1.00

1.00

 Black

1.41 (0.85–2.33)

0.18

1.64 (0.88–3.04)

0.12

 Brown

0.75 (0.45–1.27)

0.29

0.93 (0.51–1.72)

0.83

Years of education

 ≤ 5

2.17 (1.35–3.48)

< 0.01

1.91 (1.03–3.53)

0.04

 6 a 9

1.30 (0.73–2.39)

0.40

1.04 (0.47–2.26)

0.93

 ≥ 10

1.00

1.00

Year of first visit

 2004–2006

3.93 (1.87–8.26)

< 0.001

4.50 (1.80–11.23)

< 0.01

 2007–2009

2.82 (1.33–5.95)

< 0.01

2.59 (1.03–6.51)

0.04

 2010–2012

1.84 (0.83–4.08)

0.13

1.67 (0.64–4.37)

0.30

 2013–2015

1.00

1.00

-

Gender/sexual preference

 Cis-W

1.00

1.00

 Trans-W

1.05 (0.24–4.61)

0.95

2.84 (0.63–12.82)

0.17

 MSM

1.42 (0.74–2.72)

0.29

2.07 (1.01–4.24)

0.05

 MSW

2.26 (1.17–4.38)

0.02

1.92 (0.96–3.82)

0.06

ART-naïve before first visit

 No

1.00

 

1.00

1.00

 Yes

0.65 (0.42–1.03)

0.07

0.58 (0.34–0.99)

0.05

CD4 count (cells/µL)

 ≤ 50

6.82 (3.62–12.85)

< 0.0001

2.45 (1.09–5.49)

0.03

 51–200

2.65 (1.31–5.37)

< 0.01

1.16 (0.51–2.67)

0.72

 201–350

1.54 (0.68–3.47)

0.30

0.91 (0.35–2.35)

0.85

 > 350

1.00

1.00

Viral load

 < 400

1.00

 400 a 999

1.21 (0.37–3.99)

0.76

 ≥ 1.000

0.82 (0.44–1.46)

0.49

Prior AIDS-defining illness

  

 No

1.00

1.00

 Yes

5.03 (3.28–7.71)

< 0.0001

4.32 (2.33–8.00)

< 0.0001

  1. INI cohort, 2004–2015 (N = 3747)