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Table 4 Risk factors associated with LOS among inpatient and LTC post-CRPA culture: unadjusted and multivariable regression

From: Epidemiology and outcomes associated with carbapenem-resistant Acinetobacter baumannii and carbapenem-resistant Pseudomonas aeruginosa: a retrospective cohort study

Characteristics

Inpatient

[N = 3646]

 

Long-term care (LTC)

[N = 1043]

Unadjusted

IRR (95% CI)

Adjusted IRR (95% CI)

Unadjusted

IRR (95% CI)

Adjusted IRR (95% CI)

Demographic and clinical characteristics

    

 Male

0.78 (0.59–1.03)

1.39 (0.90–2.13)

 Age category

    

  18–49

Reference

Reference

 

Reference

  50–64

0.81 (0.65–1.01)

0.73 (0.59–0.90)

1.17 (0.88–1.55)

1.06 (0.81–1.40)

  65 + 

0.60 (0.49–0.74)

0.57 (0.46–0.70)

1.07 (0.82–1.40)

0.99 (0.76–1.28)

 Race

    

  White

Reference

Reference

  African American

1.14 (1.03–1.25)

0.99 (0.84–1.16)

  Other*

1.11 (0.81–1.52)

0.97 (0.56–1.67)

 Ethnicity

    

  Non-Latine

Reference

Reference

  Latine

0.91 (0.80–1.04)

0.93 (0.71–1.22)

 Region

    

  South

Reference

Reference

Reference

  Midwest

1.04 (0.93–1.15)

0.99 (0.89–1.09)

0.88 (0.74–1.05)

  West

1.24 (1.11–1.38)

1.25 (1.13–1.39)

1.01 (0.83–1.23)

  Northeast

1.01 (0.89–1.15)

1.07 (0.95–1.21)

0.82 (0.64–1.05)

  U.S. Territory

0.99 (0.83–1.17)

1.14 (0.97–1.34)

0.84 (0.60–1.19)

 Rurality

    

  Urban

Reference

Reference

  Rural

0.90 (0.77–1.06)

1.12 (0.83–1.51)

 Facility complexity

    

  High

Reference

Reference

  Low

1.21 (1.02–1.45)

1.04 (0.80–1.33)

 Specimen type

    

  Urine

Reference

Reference

Reference

Reference

  Respiratory

0.81 (0.74–0.89)

0.76 (0.69–0.83)

0.98 (0.81–1.19)

0.97 (0.80–1.17)

  Blood

0.63 (0.50–0.78)

0.67 (0.54–0.83)

1.24 (0.73–2.12)

1.02 (0.60–1.72)

  Other

1.29 (1.16–1.43)

1.27 (1.15–1.40)

1.36 (1.15–1.61)

1.38 (1.17–1.63)

Co-morbidities

    

 Charlson Score

1.02 (1.00–1.03)

1.01 (1.00–1.02)

1.01 (0.99–1.04)

0.99 (0.97–1.02)

 SCI/D

    

  No

Reference

Reference

Reference

  Yes

1.87 (1.62–2.16)

1.43 (1.23–1.65)

1.01 (0.88–1.16)

Antibiotic exposure in previous 90 days

    

 Any antibiotics

    

  No

Reference

Reference

Reference

  Yes

0.85 (0.79–0.93)

0.80 (0.68–0.95)

1.00 (0.84–1.19)

 Fluoroquinolones

    

  No

Reference

Reference

  Yes

0.82 (0.73–0.92)

0.64 (0.49–0.83)

 3rd and 4th generation cephalosporins

    

  No

Reference

Reference

  Yes

1.11 (0.88–1.41)

0.80 (0.52–1.23)

 Carbapenems

    

  No

Reference

Reference

  Yes

1.05 (0.66–1.67)

1.51 (0.31–7.37)

Length of stay 1 year prior to culture

    

 Mean, median (SD)

1.00 (1.00–1.00)

1.00 (1.00–1.00)

1.00 (1.00–1.00)

1.00 (1.00–1.00)

  1. Significant associations are shown in bold (p < 0.05)
  2. *Other includes, Asian, Native American and Pacific Islander
  3. Other specimen types include wounds, skin/soft tissue, body fluid, bone/joint, rectal cultures
  4. Respiratory specimen types include bronchial alveolar, tracheal aspirate, induced sputum, etc.