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Table 1 Rate of infection during the study period (Dec 16, 2020–Sep 30, 2021) across the four vaccination categories (excluding 309 people infected before Dec 15, 2020)

From: Continued effectiveness of COVID-19 vaccination among urban healthcare workers during delta variant predominance

Status

Person-days

No. of infections

Rate per 10,000 person-days

Unadjusted vaccine effectiveness % (95% CI)

Adjusted vaccine effectiveness % (95% CI)*

Unvaccinated

219,842

114

5.19

Reference

Reference

First dose (< 14 days)

51,329

17

3.31

44.8 (0.13–69.5)

38.8 (− 10.8–66.2)

First dose (14+ days)

51,231

7

1.37

78.9 (51.6–90.8)

75.5 (43.9–89.3)

Fully vaccinated

830,084

49

0.59

87.5 (83.0–90.8)

82.3 (75.1–87.4)

  1. Vaccine effectiveness (95% CI) derived from the Andersen–Gill extension of the Cox proportional hazards models
  2. *Adjust for age, sex, race, and the Massachusetts statewide 7-day average of new tested COVID-19 cases at the date for the first vaccine dose. Those with the race of “American Indian or Alaska Native”, “Hawaiian or Pacific Islander”, or “Two or More” were pooled into one level “other race”
  3. Not eligible for those receiving J&J/Janssen
  4. Equal or more than 14 days after single dose of Janssen vaccine/Ad26.COV2.S or having received the second shot of BNT162b2/Pfizer or mRNA-1273/Moderna