Table 1 Patient characteristics
From: Validating a clinical prediction score for Legionella-related community acquired pneumonia
Legionella CAP n = 131 | Non-Legionella CAP n = 160 | p | |
|---|---|---|---|
Male, n (%) | 88 (67.2) | 89 (55.6) | 0.037 |
Age [years], median (IQR) | 63.4 (56.2–70.3) | 72.2 (64.7–81.4) | < 0.001 |
Current smoker, n (%) | 43 (53.8) | 29 (20.1) | < 0.001 |
Comorbidities, n (%) | |||
COPD | 11 (8.4) | 47 (29.4) | < 0.001 |
Congestive heart failure | 11 (8.4) | 21 (13.1) | 0.22 |
Neurologic disease | 15 (11.5) | 37 (23.1) | 0.012 |
Cancer | 8 (6.1) | 33 (20.6) | < 0.001 |
Renal disease | 4 (3.1) | 15 (9.4) | 0.033 |
Liver disease | 4 (3.1) | 2 (1.3) | 0.271 |
Symptoms, n (%) | |||
Dyspnea | 79 (68.7) | 124 (83.8) | 0.005 |
Dry cough | 77 (58.8) | 50 (31.3) | < 0.001 |
Headache | 31 (66.0) | 14 (32.6) | < 0.001 |
Muscle or joint pain | 37 (64.9) | 25 (51.0) | 0.143 |
Nausea | 36 (52.9) | 28 (48.3) | 0.538 |
Vomiting | 28 (41.8) | 20 (37.0) | 0.686 |
Diarrhea | 42 (53.2) | 13 (15.5) | < 0.001 |
Confusion | 24 (18.3) | 32 (20.0) | 0.718 |
Physical findings, median (IQR) | |||
Heart frequency [BPM] | 100 (82–112) | 96 (83–111) | 0.635 |
Systolic blood pressure (mmHg) | 130 (118–145) | 135.5 (119–151) | 0.139 |
Diastolic blood pressure (mmHg) | 73 (65–81) | 75.5 (67–83) | 0.111 |
Body temperature (°C) | 39 (37.8–39.7) | 38.4 (37.5–39.1) | 0.002 |
CURB-65 [score 0–5], median (IQR) | 1 (0–2) | 2 (1–2) | 0.016 |
Previous antibiotic treatment, n (%) | 39 (33.6) | 42 (26.8) | 0.226 |
Laboratory findings, median (IQR) | |||
Urea (mmol/L) | 7.1 (5.5–11.4) | 7.2 (5.0–9.1) | 0.333 |
Creatinine (mc mol/L) | 101 (80–131) | 88 (66–108) | < 0.001 |
Sodium (mmol/L) | 132 (129–135) | 136 (133–138) | < 0.001 |
Potassium (mmol/L) | 3.9 (3.5–4.2) | 3.9 (3.6–4.3) | 0.186 |
Bilirubin (µmol/L) | 12 (8–19) | 13 (8–16) | 0.628 |
ASAT (IU/L) | 49 (33–103) | 26 (19–35) | < 0.001 |
ALAT (IU/L) | 36 (24–67) | 19 (13–29) | < 0.001 |
LDH (IU/L) | 465 (324–609) | 198 (168–238) | < 0.001 |
AP (IU/L) | 79 (69–115) | 82 (67–113) | 0.242 |
GGT (IU/L) | 47 (30–79) | 37 (24–67) | 0.034 |
C-reactive protein (mg/L) | 317 (244–390) | 162 (77–260) | < 0.001 |
Hemoglobin (mmol/L) | 8.3 (7.8–9.1) | 8.1 (7.3–8.9) | 0.067 |
Platelets (× 109/L) | 204 (156–249) | 221 (179–293) | 0.002 |
White blood cell count (× 109/L) | 13 (10–17) | 13 (10–18) | 0.377 |