Table 3 AUROC and calibration measures for scores and formulas from selected articles with cut-offs
qRT-PCR test | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
All | Positive | Negative | Discrimination and calibration results (Rubin’s rules) | |||||||
Calibration | ||||||||||
N | P50 (P25–P75) | N | P50 (P25–P75) | N | P50 (P25–P75) | AUROC (95CI%) | Brier score | Slope (95 CI%) | Intercept (95 CI%) | |
Vieceli et al | 1475 | 492 | 983 | |||||||
Score (0–9) | 6 (4–7) | 7 (6–9) | 4 (4–6) | 0.77 (0.74–0.79) | ||||||
Model | 0.77 (0.74–0.89) | 0.18 | 0.55 (0.48–0.62) | − 0.00 (− 0.14 to 0.14) | ||||||
Original value | 0.85 (0.77–0.92) | |||||||||
Tordjman et al | 1618 | 519 | 1099 | |||||||
Score (0–5) | 3 (2–4) | 4 (3–5) | 2 (1–4) | 0.73 (0.71–0.76) | ||||||
Model | 0.74 (0.72–0.77) | 0.19 | 0.40 (0.35–0.46) | − 0.0 (− 0.14 to 0.14) | ||||||
Original value | 0.92 (0.89–0.95) | |||||||||
Kurstjens et al | 1472 | 489 | 983 | |||||||
Score (0–14) | 6 (3–14) | 10 (7–12) | 4 (2–6) | 0.84 (0.83–0.87) | ||||||
Original value | 0.94 (0.91–0.96) | |||||||||
Aldobyany et al | 502 | 224 | 278 | |||||||
Score (0–8) | 4 (3–5) | 5 (3.5–6) | 3 (2–5) | 0.60 (0.57–0.63) | ||||||
Original value | 0.60 (0.57–0.64) | |||||||||
Nakakubo et al | 1615 | 519 | 1096 | |||||||
Score (0–11) | 4 (3–6) | 6 (5–6) | 4 (3–5) | 0.78 (0.76–0.81) | ||||||
Original value | / | |||||||||
Fink et al | 564 | 259 | 305 | 0.78 (0.75–0.80) | 0.18 | 1.13 (0.99–1.27) | 0.00 (− 0.11 to 0.11) | |||
Model | ||||||||||
Original value | 0.85 (0.81–0.90) | |||||||||