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Table 1 Descriptive analysis for all parameters used in scores/formulas, globally and by results from qRT-PCR screening test

From: Clinical prediction models for diagnosis of COVID-19 among adult patients: a validation and agreement study

 

qRT-PCR test

All

Positive

Negative

% missing

Demographics

     

 Age (years)

Total

1618

519

1099

0%

 

P50 (P25–P75)

73.00 (62–82)

72.00 (62–81)

73.00 (62–82)

 

 Gender

Total

1618

519

1099

0%

 

Male (n, %)

883 (54.6)

320 (61.7)

563 (51.2)

 
 

Female (n, %)

735 (45.4)

199 (38.3)

536 (48.8)

 

 Period

Total

1618

519

1099

0%

 

Wave 1 (n, %)

588 (36.3)

146 (28.1)

442 (40.2)

 
 

Between (n, %)

204 (12.6)

15 (2.9)

189 (17.2)

 
 

Wave 2 (n, %)

826 (51.1)

358 (69.0)

468 (42.6)

 

Comorbidities

     

 Cardiac disease

Total

593

268

325

63.3%

 

Yes (n, %)

200 (33.7)

72 (26.9)

128 (39.4)

 

 Immunosuppression

Total

593

268

325

63.3%

 

Yes (n, %)

38 (6.4)

11 (4.1)

27 (8.3)

 

 Renal failure

Total

594

268

326

63.3%

 

Yes (n, %)

48 (8.1)

17 (6.3)

31 (9.5)

 

Symptoms

     

 Fever

Total

608

272

336

62.4%

 

Yes (n, %)

282 (46.4)

169 (62.1)

113 (33.6)

 

 Dry cough

Total

607

272

335

62.4%

 

Yes (n, %)

220 (36.2)

125 (46.0)

95 (28.4)

 

 Wet cough

Total

607

272

335

 
 

Yes (n, %)

106 (17.5)

45 (16.5)

61 (18.2)

 

 Dyspnea

Total

608

272

336

62.4%

 

Yes (n, %)

403 (66.3)

192 (70.6)

211 (62.8)

 

 Diarrhea

Total

607

272

335

62.4%

 

Yes (n, %)

128 (21.1)

69 (25.4)

59 (17.6)

 

Biological parameters

     

 LDH U/L

Total

1618

519

1099

0%

 

P50 (P25–P75)

275 (219–368)

349 (267–457)

252 (205–318)

 

 CRP mg/L

Total

1618

519

1099

0%

 

P50 (P25–P75)

60.40 (15.1–140.9)

86.40 (43.6–164.2)

41.40 (9.50–129.9)

 

 Procalcitonin µg/L

Total

1615

588

202

0.2%

 

P50 (P25–P75)

0.10 (0.04–0.34)

0.13 (0.06–0.34)

0.09 (0.04–0.35)

 

 Lymphocytes 103/mm3

Total

1618

519

1099

0%

 

P50 (P25–P75)

1.01 (0.66–1.57)

0.85 (0.61–1.19)

1.12 (0.71–1.74)

 

 Basophils 103/mm3

Total

1618

519

1099

0%

 

P50 (P25–P75)

0.03 (0.01–0.05)

0.02 (0.01–0.03)

0.03 (0.02–0.05)

 

 Eosinophils 103/mm3

Total

1618

519

1099

0%

 

P50 (P25–P75)

0.03 (0.01–0.12)

0.01 (0.00–0.03)

0.07 (0.01–0.16)

 

 Ferritin µg/L

Total

1614

519

1099

0.2%

 

P50 (P25–P75)

332.5 (145.1–762.7)

702.00 (322.4–1441.4)

248.28 (108.8–530)

 

 Leukocytes 103/mm3

Total

1618

519

1099

0%

 

P50 (P25–P75)

9.40 (6.61–12.76)

7.02 (5.00–10.26)

10.40 (7.83–13.90)

 

 Neutrophils 103/mm3

Total

1618

519

1099

0%

 

P50 (P25–P75)

7.09 (4.68–10.28)

5.46 (3.50–8.51)

8.03 (5.50–11.48)

 

Chest X-ray

     

 Radiological anomaly

Total

1475

492

983

8.8%

No (n, %)

294 (19.9)

37 (7.5)

257 (26.1)

 
 

Yes (n, %)

1181 (80.1)

455 (92.5)

726 (73.9)

 

 Finding (n, %)

Total

1475

492

983

8.8%

 

No atypical signs

825 (55.9)

106 (21.5)

719 (73.1)

 
 

Subpleural or lower lung dominant distribution

104 (7.1)

56 (11.4)

48 (4.9)

 
 

Multilobar or bilateral lesion

458 (31.1)

301 (61.2)

157 (16.0)

 
 

GGO with or without consolidation

88 (6.0)

29 (5.9)

59 (6.0)

 

 Alternative diagnosis (n, %)

Total

1618

519

1099

0%

More likely other diagnosis

309 (19.1)

15 (2.9)

294 (26.8)

 
 

Hard to determine

1055 (65.2)

379 (73.0)

676 (61.5)

 
 

More likely COVID-19

254 (15.7)

125 (24.1)

129 (11.7)

 

 Other finding (n, %)

Total

1475

492

983

8.8%

 

No infiltrate

861 (58.4)

122 (24.8)

739 (75.2)

 
 

Unilateral infiltrate

129 (8.7)

48 (9.8)

81 (8.2)

 
 

Bilateral infiltrate

485 (32.9)

322 (65.4)

163 (16.6)