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Table 2 The relationship between LLV, DR and CD4 cell counts < 200 cells/μL among patients who initiated ART from 2008 to 2015

From: Impact of low-level viremia with drug resistance on CD4 cell counts among people living with HIV on antiretroviral treatment in China

Factors

N

CD4 < 200 (%)

OR (95% CI)

p

AOR (95%CI)

p

Total

6530

837

12.8%

Model 1

 VL 50–999 and No DR

1636

195

11.9%

1.0

 

1.0

 

 VL 50–999 and DR

182

58

31.9%

3.5 (2.4, 4.9)

< 0.01

3.8 (2.6, 5.5)

< 0.01

 VL < 50

3787

244

6.4%

0.5 (0.4, 0.6)

< 0.01

0.5 (0.4, 0.6)

< 0.01

 VL ≥ 1000 and No DR

430

130

30.2%

3.2 (2.5, 4.1)

< 0.01

3.1 (2.4, 4.1)

< 0.01

 VL ≥ 1000 and DR

495

210

42.4%

5.4 (4.3, 6.9)

< 0.01

5.8 (4.5, 7.4)

< 0.01

Model 2

 VL 50–200 and No DR

537

38

7.1%

1.0

 

1.0

 

 VL 201–999 and No DR

1099

157

14.3%

2.2 (1.5, 3.2)

0.14

2.4 (1.6, 3.6)

0.34

 VL 50–200 and DR

23

2

8.7%

1.3 (0.3, 5.5)

0.23

1.2 (0.3, 5.6)

0.21

 VL 201–999 and DR

159

56

35.2%

7.1 (4.5, 11.3)

< 0.01

8.0 (4.9, 13.1)

< 0.01

 VL < 50

3787

244

6.4%

0.9 (0.6, 1.3)

< 0.01

0.9 (0.6, 1.2)

< 0.01

 VL ≥ 1000 and No DR

430

130

30.2%

5.7 (3.9, 8.4)

< 0.01

5.7 (3.8, 8.5)

< 0.01

 VL ≥ 1000 and DR

495

210

42.4%

9.7 (6.7, 14.1)

< 0.01

10.7 (7.2, 15.9)

< 0.01

  1. CD4 cell counts < 200 cells/μL, CD4 cell counts < 200 cells/μL; OR, odds ratio; CI, confidence interval; AOR, adjusted odds ratio; Adjusted for: age, ethnicity, education, sex, marital status, occupation, route of HIV transmission, duration of ART, and ART regimens