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Table 4 Within-group comparison of clinical characteristics and quality of life in the exercise and control groups testing the effects of aerobic exercise among PLWHIV diagnosed with HAND

From: Effects of aerobic exercise on quality of life of people with HIV-associated neurocognitive disorder on antiretroviral therapy: a randomised controlled trial

Approach

Intention-to-treat

Per protocol

Variables

Base (n = 38)

Post-Rx (n = 38)

Follow-up (n = 38)

χ2

p

Base (n = 35)

Post-Rx (n = 24–32)

Follow-up (n = 24–32)

χ2/F

p

Mean Rank

xÌ… (SD)/Mean rank

Within exercise group

 Depression

2.12a

1.93b

1.96b

1.924

0.382

3.75 (3.02)

2.67 (3.24)

4.08 (2.93)

1.923

0.158

 ART adherence

1.98a

2.11b

1.92b

5.687

0.058

100.00 (0.00)

92.25 (2.75)

100.00 (0.00)

1.000

0.384

 Physical QoL

1.40a

2.23b

2.37b

89.177

< 0.001*

43.40 (14.22)

53.64 (12.44)

56.16 (10.44)

15.413

0.000*

 Psychological QOL

1.65a

2.11b

2.23b

35.074

< 0.001*

49.62 (15.58)

55.73 (14.25)

60.19 (11.82)

4.319

0.019*

 Social relationship

1.38a

2.35b

2.27b

91.147

< 0.001*

44.54 (19.83)

60.88 (18.58)

64.38 (18.12)

9.776

0.000*

 Environ

1.52a

2.28b

2.20b

58.045

< 0.001*

46.54 (13.43)

54.00 (12.90)

57.08 (16.81)

5.673

0.006*

 Overall QoL

1.46a

2.29b

2.25b

70.497

< 0.001*

43.07 (12.25)

52.15 (7.26)

52.56 (9.87)

8.674

0.002*

Within control group

 Depression

1.88a

2.00a

2.13a

3.082

0.214

4.24 (4.31)

5.40 (4.75)

6.16 (6.27)

0.924

0.384

 ART adherence

1.97a

1.84a

2.19b

32.947

< 0.001*

94.46 (4.33)

100.00 (0.00)

95.88 (2.28)

0.998

0.377

 Physical QoL

1.97a

1.83a

2.20b

11.230

0.004

50.41 (16.54)

47.41 (4.29)

52.04 (12.14)

1.048

0.358

 Psychological QOL

2.01a

1.94a

2.0a

1.102

0.576

56.56 (15.22)

54.26 (14.06)

55.44 (17.26)

0.191

0.780

 Social relationship

2.37a

1.51a

2.12b

58.482

< 0.001*

57.69 (17.31)

50.08 (18.15)

52.65 (22.50)

1.668

0.199

 Environ

2.04a

1.69a

2.27b

27.375

< 0.001*

50.85 (14.47)

45.77 (15.34)

50.85 (16.18)

1.412

0.253

 Overall QOL

2.11a

1.76b

2.12ac

13.149

0.001

50.23 (8.28)

45.77 (15.34)

50.00 (8.44)

1.882

0.180

  1. χ2: Chi-square from Friedman’s test; F: F-value from repeated measure ANOVA. NB: intention-to-treat data were log-transformed; Superscripts a, b & c indicates Wilcoxon post-hoc pair-wise comparison. The sameness of superscripts indicate no significant difference between pairs; while a difference of superscripts indicates significant differences between given pairs
  2. *: significant at alpha = 0.05