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Table 3 Clinical characteristics and quality of life at 3 months follow up between exercise and control groups comparing the effects of aerobic exercise on PLWHIV diagnosed with HAND

From: Effects of aerobic exercise on quality of life of people with HIV-associated neurocognitive disorder on antiretroviral therapy: a randomised controlled trial

Approach

Intention-to-treat

Per protocol

Variables

Exercise

(n = 38)

MR (SE)

Control

(n = 35)

MR (SE)

F

p

Exercise (n = 24–32)

MR/xÌ… (SD)

Control (n = 24–33)

MR/xÌ…(SD)

F

p

ART Adherence

128.99a (5.61)

118.76a (5.79)

1.608

0.206

30.98

29.05

406.50

0.321

Depression (BDI)

98.78a (6.48)

124.21a (6.74)

7.406

0.007*

27.95

33.05

373.50

0.255

SPO2

40.45b (2.35)

36.92b (2.43)

1.085

0.298

28.26

24.87

293.50

0.410

Heart rate

3.17c (0.11)

2.91c (0.12)

2.726

0.100

73.30 (13.68)

70.71 (13.53)

0.679

0.500

SBP

17.44d (1.33)

13.40d (1.39)

4.418

0.036*

25.33

26.59

308.00

0.758

DBP

5.50d (0.42)

6.03d (0.44)

0.792

0.374

25.52

25.48

310.00

0.992

Physical QoL

130.47a (6.78)

107.77a (6.97)

5.470

0.020*

32.76

26.24

326.00

0.134

Psychological QOL

135.39a (6.80)

108.70a (7.09)

7.388

0.007*

32.08

27.84

372.50

0.338

Social relationship

62.35ae (4.80)

53.59ae (4.82)

1.659

0.199

33.33

25.67

309.50

0.081

Environment

128.04a (6.92)

111.72a (6.96)

2.765

0.097

58.24 (17.12)

50.76 (15.94)

1.722

0.091

Overall QOL

7.68af (0.46)

6.48af (0.47)

3.301

0.070

53.23 (9.62)

49.90 (8.23)

1.429

0.158

  1. x̅(SD): mean (standard deviation); BDI: Beck depression inventory; MR(SE): Mean rank (standard error); MWU: Man-Whitney test; t: t-value; Superscripts—a: controlled for baseline difference in ART adherence; b: controlled for baseline differences in SPO2, c: controlled for baseline differences in pulse rate; d: controlled for baseline differences in diastolic blood pressure; e: controlled for baseline differences in social relationship QoL; f: controlled for baseline differences in overall QoL
  2. *: significant at alpha = 0.05
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BMC Infectious Diseases

ISSN: 1471-2334

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