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Table 2 The clinical characteristics and quality of life of PLWHIV diagnosed with HAND following a 12-week aerobic exercise programme

From: Effects of aerobic exercise on quality of life of people with HIV-associated neurocognitive disorder on antiretroviral therapy: a randomised controlled trial

Approach

Intention-to-treat

Per protocol

Variables

Exercise (n = 38)

MR (SE)

Control (n = 38)

MR (SE)

MWU

p

Exercise

n = 24–32)

MR/xÌ… (SE)

Control

(n = 24–33)

MR/xÌ… (SE)

F

p

Depression score

83.84a (6.40)

101.90a (5.91)

4.30

0.039*

22.56

32.44

231.00

0.020*

ART adherence

115.34a (6.27)

113.98a (6.26)

0.02

0.878

21.71

23.00

216.00

0.208

SPO2

3.24b (0.095)

2.77b (0.098)

11.54

0.001*

31.29

27.71

368.50

0.388

Heart rate

6.61c (0.43)

4.95c (0.45)

7.16

0.008*

75.98 (11.20)

71.20 (10.53)

1.690

0.096

Systolic BP

6.37d (0.44)

5.35d (0.45)

2.63

0.106

103.39 (13.73)

110.48 (12.17)

− 2.030

0.047*

Diastolic BP

3.07d (0.11)

3.01d (0.11)

0.12

0.725

25.91

30.02

321.50

0.337

Physical QoL

131.78a (6.72)

100.53a (6.75)

10.75

0.001*

34.76

25.40

297.00

0.034*

Psychological QOL

127.59a (6.67)

101.95a (6.83)

7.22

0.008*

55.83 (13.79)

51.57 (15.85)

1.100

0.276

Social relationship QoL

19.63ae (1.23)

13.31ae (1.29)

12.62

0.266

35.84

23.16

236.50

0.004*

Environmental QoL

127.62a (6.61)

97.07a (6.69)

10.54

0.001*

53.97 (15.02)

46.17 (14.62)

2.003

0.050

Overall QoL

7.82af (0.43)

5.74af (0.44)

11.43

0.001*

51.83 (7.20)

45.93 (8.40)

2.889

0.005*

  1. Data are shown for the exercise and control groups immediately after the exercise programme
  2. x̅ (SD): mean (standard deviation); BDI: Beck depression inventory; MR(SE): Mean rank (standard error); MWU: Man–Whitney test; t: t-value; Superscripts—a: controlled for baseline difference in ART adherence; b: controlled for baseline differences in SPO2, c: controlled for baseline differences in pulse rate; d: controlled for baseline differences in diastolic blood pressure; e: controlled for baseline differences in social relationship QoL; f: controlled for baseline differences in overall QoL
  3. *: significant at alpha = 0.05
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BMC Infectious Diseases

ISSN: 1471-2334

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