Table 1 Summary of all reported cases of spine-involved mucormycosis
From: Paraplegia secondary to disseminated mucormycosis: case report and literature review
Number | Year | Author | Age/sex | Presenting symptoms | Spinal involvement Position | Underlying conditions | Treatment | Primary lesion | Outcome |
|---|---|---|---|---|---|---|---|---|---|
1 | 2018 | Present | 48/M | Paralysis, fever | T3–T6 | Diabetic ketoacidosis | Surgical debridement, posaconazole, amphotericin B liposomes, spinal canal decompression, pedicle screw fixation | Lung | Dead |
2 | 2017 | Shah et al. [20] | 54/M | Mechanical low back pain, right lower limb radiation | L3–L4 | Cryptogenic liver cirrhosis, | Liposomal Amphotericin B | None | Dead |
3 | 2016 | Wang et al. [16] | 20/F | Lower extremity numbness and weakness fever, dysuria | T3–T6 | Right lung pneumonectomy | Amphotericin B | Chest wall | Live |
4 | 2015 | Navanukroh et al. [13] | 42/F | Dry cough, left buttock and left lower limb sharp shooting pain, fever | S1 | Kidney transplantation | Decompressive laminectomy of two segments, liposomal amphotericin B | Lung | Live |
5 | 2015 | Hadgaonkar et al. [8] | 64/M | Low back pain, fever, weight loss | L4, L5 | Diabetes mellitus, hypertension, chronic kidney disease | Amphotericin B | None | Dead |
6 | 2010 | Giuliani et al. [5] | 54/F | Paraparesis | T10–T12 | Acute septic panniculitis, decompensated Diabetes mellitus, obliterant arteriopathy | Acyclovir, Liposomal Amphotericin B | None | Live |
7 | 2006 | Chen et al. [12] | 57/F | Low back pain, fever, weakness and numbness of the lower extremities | L4, L5 | None | Surgical debridement, amphotericin-B | None | Live |
8 | 2000 | Machida et al. [11] | 58/M | Fever, paraplegia | T12, L1 | Acute myelocytic leukemia | Broad-spectrum antibiotics, amphotericin-B Local irradiation | Lung | Dead |
9 | 1996 | Pohle et al. [19] | 43/M | Lower extremity weakness, fever, weight loss | T3, T4 | Diabetic ketoacidosis, pancreatitis | Amphotericin B | Lung | Dead |
10 | 1988 | Rozich et al. [14] | 52/M | Back pain, lower extremity weakness, fever | L1–L2 | MDS, splenectomy | Amphotericin B, Surgical debridement | Lung | Dead |
11 | 1979 | Buruma et al. [10] | 60/M | Neck pain, arm weakness | C3, C4 | Carcinoma of the hypopharynx | None | None | Dead |