From: Diagnostic and therapeutic challenges of treating opportunistic fungal cellulitis: a case series
 | Underlying condition | Immuno- suppression | Atypical features of cellulitis | Fungal Pathogen | Antifungal regimen | Outcome | Relevant citations for other related case reports |
---|---|---|---|---|---|---|---|
Patient 1 | B cell ALL s/p allo-HSCT c/b cGVHD | Prednisone 10Â mg daily, ruxolitinib 10Â mg twice daily | Ulcerative lesion on dorsum of foot unresponsive to antibiotics | Fusarium solani | 5 weeks of IV amphotericin B 5Â mg/kg daily and voriconazole 4Â mg/kg twice daily | Near baseline (residual scarring) | |
Patient 2 | Systemic scleroderma c/b interstitial pneumonia s/p bilateral lung transplant | Azathioprine 50Â mg daily, prednisone 5Â mg twice daily | Ulcerative lesion on dorsum of foot unresponsive to antibiotics | Fusarium solani | Amphotericin B 5Â mg/kg daily and voriconazole 4Â mg/kg twice daily | Deceased (refractory septic shock) | |
Patient 3 | Alport Syndrome c/b ESRD s/p kidney transplant | Azathioprine 100Â mg daily, tacrolimus 2Â mg daily | Numerous violaceous papules on calf and dorsum of foot unresponsive to antibiotics | Purpureocillium lilacinum | 8 weeks of itraconazole 200Â mg twice daily | Recurrence after discontinuation of itraconazole, responded to posaconazole |