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Table 1 Summary of case reports

From: Diagnostic and therapeutic challenges of treating opportunistic fungal cellulitis: a case series

 

Underlying condition

Immuno- suppression

Atypical features of cellulitis

Fungal Pathogen

Antifungal regimen

Outcome

Relevant citations for other related case reports

Patient 1

B cell ALL s/p allo-HSCT c/b cGVHD

Prednisone 10 mg daily, ruxolitinib 10 mg twice daily

Ulcerative lesion on dorsum of foot unresponsive to antibiotics

Fusarium solani

5 weeks of IV amphotericin B 5 mg/kg daily and voriconazole 4 mg/kg twice daily

Near baseline (residual scarring)

[4, 5, 18, 19, 22]

Patient 2

Systemic scleroderma c/b interstitial pneumonia s/p bilateral lung transplant

Azathioprine 50 mg daily, prednisone 5 mg twice daily

Ulcerative lesion on dorsum of foot unresponsive to antibiotics

Fusarium solani

Amphotericin B 5 mg/kg daily and voriconazole 4 mg/kg twice daily

Deceased (refractory septic shock)

[4, 5, 18, 19, 23]

Patient 3

Alport Syndrome c/b ESRD s/p kidney transplant

Azathioprine 100 mg daily, tacrolimus 2 mg daily

Numerous violaceous papules on calf and dorsum of foot unresponsive to antibiotics

Purpureocillium lilacinum

8 weeks of itraconazole 200 mg twice daily

Recurrence after discontinuation of itraconazole, responded to posaconazole

[3, 6, 9, 12, 13, 18, 19]

  1. ALL acute lymphoblastic leukemia, s/p status post, allo-HCT allogeneic hematopoietic cell transplantation, c/b complicated by, cGVHD chronic graft versus host disease, ESRD end-stage renal disease