Fig. 1

Lineage and Sublineage Analysis of 161 Cases of M.tb Clinical strains. A The phylogenetic tree of 161 cases of M.tb clinical strains in Kashgar prefecture (including one city and six counties) was constructed by the ML method. A total of 3 lineages (Lineage 2-Lineage 4, marked with orange, green and blue, respectively) and 11 sublineages (marked by the shaded areas) were defined, and among them, the Lineage 3 sublineage was designated in an anticlockwise order (as Lineage 3.2 and Lineage 3.3, respectively), while the N 161 cases of M.tb clinical strains were marked with black font. Excluding Lineage 2.2.2 sublineages, all clinical strains in M.tb Lineage 2 were of Lineage 2.2.1 sublineages. B The proportion of 9 sublineages of M.tb clinical strains. C PCA diagram of M.tb clinical strains of the three lineages. D PCA diagram of M.tb clinical strains in Lineage 2. E PCA diagram of M.tb clinical strains in Lineage 3. F PCA diagram of M.tb clinical strains in Lineage 4