Enigma of COVID-19: is “multisystem inflammatory syndrome in adults” (MIS-A) predictable?

BMC Infectious Diseases

Table 4 Independent predictors of MIS-A and mortality

	HR	95% CI	p
Model I
Gender
Female	Ref
Male	1.39	1.06–1.82	0.019
Presence of typical COVID-19 Involvement	3.37	1.96–5.79	< 0.001
Platelet	0.98	0.97–0.99	0.026
LLR	2.48	1.98–3.09	< 0.001
CRP	1.03	1.03–1.06	< 0.001
	− 2Log Likelihood = 3293.5; p < 0.001
Model II
Gender
Female	Ref
Male	1.65	1.17–2.32	0.004
Presence of typical COVID-19 Involvement	4.1	2.01–8.37	< 0.001
LLR	4.82	1.70–13.65	0.003
CRP	1.03	1.01–1.05	0.023
	− 2Log Likelihood = 3293.5; p < 0.001
Model III
Age	1.03	1.02–1.04	< 0.001
LLR	1.44	1.13–1.84	0.003
CRP	1.05	1.03–1.07	< 0.001
MIS-A	4.77	3.20–7.09	< 0.001
	− 2Log Likelihood = 1941.4; p < 0.001
Model IV
Age	1.03	1.01–1.04	0.003
LLR	1.37	1.05–1.80	0.023
CRP	1.04	1.02–1.07	0.001
	− 2Log Likelihood = 718.3; p < 0.001

Model I: Factors predicting MIS-A development in the whole population
Model II: Factors predicting MIS-A development in surviving patients
Model III: Factors predicting mortality in the whole population
Model IV: Factors predicting mortality in MIS-A patients
MIS-A multisystem inflammatory in adults, HR hazard ratio, CI confidence interval, LLR LDH / lymphocyte ratio, CRP C-reactive protein

ISSN: 1471-2334