Table 2 Diagnostic performance of FECT, STST, BCT, APC and RT-PCR in S. stercoralis detection against the composite reference
Methods | SN (95% CI) | SP (95% CI) | PPV (95% CI) | NPV (95% CI) | Kappa value | χ2, p-value | ||
|---|---|---|---|---|---|---|---|---|
Composite reference | ||||||||
Pos (N) | Neg (N) | |||||||
FECT | ||||||||
Pos | 17 | 0 | 5.2 (3.0–8.14) | 100 (99.3–100) | 100.00 | 5.3 (5.1–5.4) | 0.062 | 27.2, 0.000 |
Neg | 312 | 515 | ||||||
STST | ||||||||
Pos | 34 | 0 | 10.3 (7.3–14.1) | 100 (99.3–100) | 100.00 | 5.5 (5.4–5.7) | 0.123 | 55.5, 0.000 |
Neg | 295 | 515 | ||||||
BCT | ||||||||
Pos | 87 | 0 | 26.4 (21.8–31.6) | 100 (99.3–99.5) | 100.00 | 6.7 (6.3–7.1) | 0.305 | 151.4, 0.000 |
Neg | 242 | 515 | ||||||
APC | ||||||||
Pos | 92 | 0 | 28.0 (23.2–33.2) | 100 (99.3–100) | 100.00 | 6.8 (6.4–7.3) | 0.321 | 161.6, 0.000 |
Neg | 237 | 515 | ||||||
RT-PCR | ||||||||
Pos | 243 | 0 | 73.9 (68.8–78.5) | 100 (99.3–100.0) | 100.00 | 16.8 (14.4–19.5) | 0.775 | 534.2, 0.000 |
Neg | 86 | 515 | ||||||