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Table 1 Demographic and clinical characteristics of recipients and donors

From: Recipient and donor PTX3 rs2305619 polymorphisms increase the susceptibility to invasive fungal disease following haploidentical stem cell transplantation: a prospective study

Variables

Total number (n = 251)

Recipient age (y), median

28 (2–63)

 Children ( 16)

70 (27.9%)

 Adults (> 16)

181 (72.1%)

Male sex, n (%)

140 (55.8%)

Underling disease (%)

 AML

102 (40.6%)

 ALL

99 (39.4%)

 AA

20 (8.0%)

 MDS

19 (7.6%)

 Others

11 (4.4%)

Donor age (y), median

36 (4–64)

Male donor sex, n (%)

190 (75.7%)

Donor–recipient ABO blood type

 Match, n (%)

138 (55.0%)

 Major mismatch, n (%)

53 (21.1%)

 Minor mismatch, n (%)

60 (23.9%)

Mononuclear cells (× 108/kg)

8.74 (6.16–13.97)

CD34+ cells (× 106/kg)

2.76 (0.68–6.03)

IFD prophylaxis

 Fluconazole

9 (3.6%)

 Itraconazole

181 (72.1%)

 Voriconazole

53 (21.1%)

 Caspofungin

8 (3.2%)

  1. AML acute myeloid leukemia, ALL acute lympphocytic leukemia, AA aplastic anemia, MDS myelodysplastic syndrome, IFD invasive fungal disease