Fig. 1

The clinical characteristics of patients with concomitant skin and soft tissue infections. A The ratio of patients who with SSTIs, and the mortality rates of patients with and without SSTIs. B The patients’ lower limbs showed swelling with massive subcutaneous bruising and blister formation. C The patient with bilateral swelling of the lower extremities and massive subcutaneous bruising with blister formation bilaterally around navel and groin. The perineum and scrotum were swollen with bruising. D Depiction of the possible mechanism by which Aeromonas causes skin and soft tissue infection through bloodstream infection. Necrotizing soft tissue infection often involves limbs, perineum, and abdomen. The lower extremities are most commonly involved and may present with erythema, severe pain, skin bullae, necrosis, or ecchymosis