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Table 2 Factors associated with multi-drug resistant isolates identified from the specimens of bone and skin and soft tissues of patients with war-related injuries

From: Antibiotic resistance among bacteria isolated from war-wounded patients at the Weapon Traumatology Training Center of the International Committee of the Red Cross from 2016 to 2019: a secondary analysis of WHONET surveillance data

Factor

MDR

(N = 186)

n (%)

Unadjusted OR (95% CI)*

p-value**

Adjusted OR (95% CI)†

p-value**

Sociodemographics

 Age

–

0.993 (0.978, 1.009)

0.389

0.998 (0.980, 1.016)

0.786

 Sex

     

  Male

156 (83.9)

1

0.410

1

0.480

  Female

30 (16.1)

0.789 (0.449, 1.386)

 

0.791 (0.412, 1.518)

 

 Nationality

     

  Syria

135 (72.6)

1

0.006

1

0.026

  Iraq

23 (12.4)

5.28 (1.777, 15.699)

 

5.899 (1.848, 18.835)

 

  Lebanon

9 (4.8)

0.636 (0.263, 1.539)

 

0.624 (0.228, 1.712)

 

  Palestine

10 (5.4)

1.837 (0.611, 5.523)

 

1.597 (0.448, 5.698)

 

  Yemen

9 (4.8)

4.133 (0.876, 19.5)

 

1.964 (0.364, 10.612)

 

Specimen

 Bacteria

     

  S. aureus

83 (44.6)

1

 < 0.001

1

 < 0.001

  Enterobacterales

83 (44.6)

5.5 (2.978, 10.15)

 

5.662 (2.981, 10.755)

 

  P. aeruginosa

14 (7.6)

0.464 (0.231, 0.93)

 

0.427 (0.204, 0.893)

 

  A. baumannii

3 (1.6)

0.795 (0.173, 3.66)

 

0.801 (0.163, 3.941)

 

  Enterococci

3 (1.6)

0.398 (0.102, 1.55)

 

0.361 (0.085, 1.532)

 

 Site

     

  SST

97 (52.2)

1

0.051

1

0.071

  Bone

89 (47.8)

1.551 (0.999, 2.410)

 

1.590 (0.961, 2.632)

 

 Year of collection

     

2016

46 (24.7)

1

0.432

1

0.723

2017

56 (30.1)

1.187 (0.659, 2.319)

 

1.181 (0.59, 2.367)

 

2018

47 (25.3)

1.328 (0.710, 2.484)

 

1.18 (0.564, 2.467)

 

2019

37 (19.9)

0.804 (0.433, 1.495)

 

0.819 (0.400, 1.678)

 
  1. CI confidence interval, MDR multi-drug resistant, OR odds ratio, SST skin and soft tissue
  2. *Univariate logistic regression models were conducted
  3. **p-value from Likelihood Ratio Test
  4. †Multivariable logistic regression model was conducted