From: Severe and critical COVID-19 in a tertiary center in Colombia, a retrospective cross-sectional study
Variable | n = 158 (%) | Patients discharged alive n = 101(%) | In-hospital death n = 57(%) | p | Patients not needing invasive mechanical ventilation, n = 95(%) | Patients requiring invasive mechanical ventilation, n = 63(%) | p |
---|---|---|---|---|---|---|---|
Charlson comorbidity index, median (IQR) | 3 (1–4) | 2 (1–3) | 4 (2.5–6) | 0.001 | 2 (1–4) | 3 (2–5) | 0.033 |
Charlson ≥ 3 points | 86 (54.4) | 43 (42.6) | 43 (75.4) | 0.001 | 47 (49) | 39 (61) | 0.12 |
News2 score, median (IQR) | 7 (5–9) | 6 (5–8) | 9 (7–11) | 0.001 | 6 (5–8) | 8 (7–11) | 0.001 |
News2 score: ≥ 7 points | 92 (58.2) | 46 (45.5) | 46 (80.7) | 0.001 | 39 (41) | 53 (84) | 0.001 |
MuLBSTA score, median (IQR) | 9 (7–13) | 9 (5.5–11) | 11 (9–15) | 0.001 | 9 (5–13) | 11 (9–13) | 0.001 |
MuLBSTA score, > 10 points | 76 (48.1) | 37 (36.6) | 39 (68.4) | 0.001 | 41 (43) | 35 (55) | 0.1 |
qSOFA score, 2–3 points | 42 (26.6) | 10 (9.9) | 32 (56.1) | 0.001 | 10 (10) | 32(50) | 0.001 |
PSI/PORT score, median (IQR) | 90 (70–112) | 79 (64.5–95.5) | 112 (94–141) | 0.001 | 79 (64–98) | 105 (89–127) | 0.001 |
PSI/PORT score, < 71 points | 41 (25.9) | 38 (37.6) | 3 (5.3) | 0.001 | 36 (37.9) | 5 (7.9) | 0.001 |
PSI/PORT score, 71–90 points | 39 (24.7) | 31 (30.7) | 8 (14) | 0.02 | 28 (29) | 11 (17) | 0.08 |
PSI/PORT score, 91–130 points | 57 (36.1) | 27 (26.7) | 30 (52.6) | 0.001 | 23 (24) | 34 (54) | 0.00 |
PSI/PORT score, > 130 points | 21 (13.3) | 5 (5) | 16 (28.1) | 0.001 | 8 (8) | 13 (20) | 0.02 |
APACHE II Score upon admission, median (IQR) | 10 (7–14) | 9 (7–13) | 13 (10.5–18.5) | 0.001 | 9 (7–13) | 12 (10–18) | 0.001 |
APACHE II score, ≥ 10 points | 94 (59.5) | 45 (44.6) | 49 (86) | 0.001 | 45 (47) | 49 (77) | 0.001 |
SOFA score, median (IQR) | 3 (2–6) | 2 (2–4) | 5 (3.5–7.5) | 0.001 | 2 (2–4) | 5 (3–7) | 0.001 |
SOFA score, ≥ 4 points | 75 (47.5) | 32 (31.7) | 43 (75.4) | 0.001 | 28 (29) | 47 (74) | 0.001 |
CURB 65 score, median (IQR) | 2 (1–2) | 1 (1–2) | 2 (2–3) | 0.001 | 1 (1–2) | 2 (1–3) | 0.001 |
CURB 65 score, 0–1 points | 72 (45.6) | 61 (60) | 11 (19) | 0.001 | 56 (58) | 16 (25) | 0.001 |
CURB 65 score, 2 points | 56 (35.4) | 34 (33.7) | 22 (38.6) | 0.5 | 33 (34) | 23 (36) | 0.8 |
CURB 65 score, 3–5 points | 30 (19) | 6 (5.9) | 24 (42.1) | 0.001 | 6 (6) | 24 (38) | 0.001 |