Table 1 Characteristics of 336 bacteraemia patients and 336 controls matched for sex, year of birth, and date of culture: Alicante, Spain, 2016–2017
Bacteraemia patients (N = 336) | Control patients (N = 336) | p value | |
|---|---|---|---|
Gender, n (%) | |||
Men | 151 (44.9) | 151 (44.9) | |
Women | 185 (55.1) | 185 (55.1) | |
Age in years, median (IQR) | 86 (82–89) | 86 (82–89) | |
Age group, n (%) | |||
80–89 years | 258 (76.8) | 258 (76.8) | |
≥ 90 years | 78 (23.2) | 78 (23.2) | |
Clinical situation, n (%) | |||
Glasgow Coma Scale < 15 | 98 (29.3) | 85 (25.3) | 0.30 |
Respiratory rate > 22 brpm | 63 (18.8) | 62 (18.5) | 1.00 |
Systolic blood pressure < 100 mmHg | 82 (24.3) | 54 (16.1) | 0.010* |
qSOFA ≥ 2 | 73 (21.7) | 43 (12.8) | 0.003* |
Biochemistry, n (%) | |||
Kidney injury * | 253 (75.3) | 222 (66.3) | 0.013* |
Natremia > 145 mmol/L | 28 (8.3) | 32 (9.5) | 0.69 |
One-month follow-up | |||
Days of follow-up, median (IQR) | 30 (30–30) | 30 (30–30) | |
Person-years at risk | 23.36 | 24.77 | |
Mortality rate per person-year (95% CI) | 3.08 (2.47–3.85) | 1.97 (1.26–2.24) | |
Deaths, n (%) | 72 (21.4) | 49 (14.6) | 0.027* |
One-year follow-up | |||
Days of follow-up, median (IQR) | 365 (40–365) | 365 (149–365) | |
Person-years at risk | 218.93 | 249.37 | |
Mortality rate per person-year (95% CI) | 0.69 (0.58–0.80) | 0.46 (0.39–0.56) | |
Deaths, n (%) | 152 (45.2) | 117 (34.8) | 0.007* |
Microorganisms, n (%) | |||
Escherichia coli | 145 (43) | - | |
Enterococcus spp. | 39 (12.4) | - | |
Klebsiella spp. | 35 (10.4) | - | |
Streptococcus pneumoniae | 15 (4.5) | - | |
Proteus mirabilis | 15 (4.5) | - | |
Coagulase-negative staphylococci | 15 (4.5) | - | |
Other Enterobacteriaceae | 15 (4.5) | - | |
Staphylococcus aureus | 12 (3.6) | - | |
Pseudomonas aeruginosa | 9 (2.7) | - | |
Source | |||
Urinary tract | 149 (44.3) | - | |
Lower respiratory tract | 70 (20.8) | - | |
Biliary tract | 31 (9.3) | - | |
Primary bacteraemia | 30 (8.9) | - | |
Intra-abdominal | 19 (5.7) | - | |
Skin and soft tissue | 15 (4.5) | - | |
Catheter-related infection | 16 (4.8) | - | |
Other | 6 (1.8) | - | |