|
Variable/category
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
|---|
|
MP dose
| |
0.0246
| |
0.0237
|
|
LD MP vs NMP
|
0.16 (0.04,0.62)
|
0.0080
|
0.13 (0.03,0.61)
|
0.0101
|
|
HD MP vs NMP
|
0.24 (0.06,0.92)
|
0.0371
|
0.15 (0.04,0.64)
|
0.0106
|
|
HD MP vs LD MP
|
1.52 (0.45,5.12)
|
0.5005
|
1.21 (0.42,3.49)
|
0.7287
|
|
Diabetes
|
1.38 (0.54,3.54)
|
0.5023
| | |
|
Hypertension
|
2.40 (0.83,6.91)
|
0.1047
| | |
|
Chronic kidney disease
|
4.77 (1.96,11.62)
|
0.0006
|
6.36 (1.87,21.67)
|
0.0031
|
|
Male vs female
|
0.58 (0.23,1.45)
|
0.2421
| | |
|
Respiratory rate > 22 bpm
|
1.24 (0.50,3.08)
|
0.6489
| | |
|
Older age ≥ 60 years
|
9.45 (1.22,72.98)
|
0.0313
| | |
|
Obesity status BMI ≥ 30 kg/m2
|
1.61 (0.66,3.92)
|
0.2922
| | |
|
Cancer
|
1.19 (0.24,5.80)
|
0.8297
| | |
|
CRP > 20 mg/L
|
4.46 (1.64,12.10)
|
0.0033
|
5.02 (1.72,14.66)
|
0.0032
|
|
Ferritin ≥ 1400 μg/L
|
0.35 (0.12,1.03)
|
0.0577
| | |
|
Supplemental oxygen
| |
0.5732
| | |
|
NMV vs none
|
1.96 (0.56,6.87)
|
0.2914
| | |
|
MV vs none
|
1.66 (0.38,7.26)
|
0.5015
| | |
|
qSOFA
| |
0.5020
| | |
|
qSOFA 1 vs 0
|
0.90 (0.37,2.22)
|
0.8251
| | |
|
qSOFA 2 vs 0
|
2.43 (0.45,13.04)
|
0.2987
| | |
|
Creatinine ≥ 1.5 mg/dL
|
2.26
(0.85,6.03)
|
0.1031
| | |
- Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
- MV mechanical ventilation; NMV non-mechanical ventilation; HR hazard ratio; CI confidence interval
