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Table 4 Univariable and multivariate analysis of in-hospital survival in admitted COVID-19 Hispanic patients (n = 251)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Variable/Category Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
MP dose   0.0032   
 LD MP vs none 0.35 (0.18,0.67) 0.0015   
 HD MP vs none 0.72 (0.40,1.29) 0.2703   
 HD MP vs LD MP 2.08 (1.22, 3.54) 0.0073   
Diabetes 1.20 (0.76,1.89) 0.4400   
Hypertension 2.65 (1.66,4.24) < 0.0001 2.52 (1.14,4.47) 0.0012
Chronic kidney disease 2.65 (1.38,5.09) 0.0034   
Male vs female 1.38 (0.87,2.18) 0.1688   
Respiratory rate > 22 bpm 1.01 (0.59,1.72) 0.9774   
Older age ≥ 60 years 2.56 (1.55,4.23) 0.0002   
Obesity status BMI ≥ 30 kg/m2 0.75 (0.48,1.17) 0.2052   
Cancer 2.51 (1.19,5.27) 0.0154 3.04 (1.16,8.02) 0.0244
CRP > 20 mg/L 1.32 (0.84,2.08) 0.2324   
D-dimer ≥ 2 mcg/mL 1.79 (1.05,3.04) 0.0320 2.21 (1.23,3.96) 0.0077
Ferritin ≥ 1400 μg/L 1.30 (0.81,2.11) 0.2806   
Supplemental oxygen   0.2827   
 NMV vs none 1.19 (0.63,2.25) 0.5961
 MV vs none 0.73 (0.35,1.53) 0.3989   
qSOFA   0.0142
 qSOFA rec 1 vs 0 0.74 (0.43,1.27) 0.2751
 qSOFA rec 2 vs 0 1.99 (1.11,3.55) 0.0202
Creatinine ≥ 1.5 mg/dL 2.16 (1.20,3.89) 0.0100
  1. Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
  2. MV mechanical ventilation; NMV non-mechanical ventilation; HR hazard ratio; CI confidence interval