|
Variable/Category
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
|---|
|
MP dose
| |
0.0032
| | |
|
LD MP vs none
|
0.35 (0.18,0.67)
|
0.0015
| | |
|
HD MP vs none
|
0.72 (0.40,1.29)
|
0.2703
| | |
|
HD MP vs LD MP
|
2.08 (1.22, 3.54)
|
0.0073
| | |
|
Diabetes
|
1.20 (0.76,1.89)
|
0.4400
| | |
|
Hypertension
|
2.65 (1.66,4.24)
|
< 0.0001
|
2.52 (1.14,4.47)
|
0.0012
|
|
Chronic kidney disease
|
2.65 (1.38,5.09)
|
0.0034
| | |
|
Male vs female
|
1.38 (0.87,2.18)
|
0.1688
| | |
|
Respiratory rate > 22 bpm
|
1.01 (0.59,1.72)
|
0.9774
| | |
|
Older age ≥ 60 years
|
2.56 (1.55,4.23)
|
0.0002
| | |
|
Obesity status BMI ≥ 30 kg/m2
|
0.75 (0.48,1.17)
|
0.2052
| | |
|
Cancer
|
2.51 (1.19,5.27)
|
0.0154
|
3.04 (1.16,8.02)
|
0.0244
|
|
CRP > 20 mg/L
|
1.32 (0.84,2.08)
|
0.2324
| | |
|
D-dimer ≥ 2 mcg/mL
|
1.79 (1.05,3.04)
|
0.0320
|
2.21 (1.23,3.96)
|
0.0077
|
|
Ferritin ≥ 1400 μg/L
|
1.30 (0.81,2.11)
|
0.2806
| | |
|
Supplemental oxygen
| |
0.2827
| | |
|
NMV vs none
|
1.19 (0.63,2.25)
|
0.5961
|
|
MV vs none
|
0.73 (0.35,1.53)
|
0.3989
| | |
|
qSOFA
| |
0.0142
|
|
qSOFA rec 1 vs 0
|
0.74 (0.43,1.27)
|
0.2751
|
|
qSOFA rec 2 vs 0
|
1.99 (1.11,3.55)
|
0.0202
|
|
Creatinine ≥ 1.5 mg/dL
|
2.16 (1.20,3.89)
|
0.0100
|
- Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
- MV mechanical ventilation; NMV non-mechanical ventilation; HR hazard ratio; CI confidence interval
