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Table 3 Univariable and multivariable analysis of in-hospital survival in admitted COVID-19 white patients (n = 338)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Variable/Category Univariate analysis Multivariable analysis
HR (95% CI) P value HR (95% CI) P value
MP dose   < 0.0001    < 0.0001
 LD MP vs NMP 0.35 (0.22,0.56)  < 0.0001 0.37 (0.23,0.59) < 0.0001
 HD MP vs NMP 0.55 (0.34,0.88) 0.0132 0.56 (0.35,0.91) 0.0183
 HD MP vs LD MP 1.56 (0.94,2.57) 0.0855 1.53 (0.91, 2.56) 0.1076
Diabetes 1.05 (0.72,1.51) 0.8124   
Hypertension 2.03 (1.36,3.05) 0.0006   
Chronic kidney disease 1.66 (1.01,2.73) 0.0468   
Male vs female 1.38 (0.94,2.03) 0.1050   
Respiratory rate > 22 bpm 1.66 (1.07,2.57) 0.0232   
Older age ≥ 60 years 2.22 (1.31,3.75) 0.0030   
Obesity status BMI ≥ 30 kg/m2 1.05 (0.73,1.51) 0.8053   
Cancer 1.90 (1.24,2.92) 0.0032 1.68 (1.03,2.69) 0.0376
CRP > 20 mg/L 0.77 (0.45,1.33) 0.3500   
Ferritin ≥ 1400 μg/L 1.11 (0.74,1.67) 0.6028   
Supplemental oxygen   0.0593   
 NMV vs none 1.33 (0.72,2.47) 0.3661   
 MV vs none 1.72 (1.09,2.71) 0.0194   
qSOFA    < 0.0001    < 0.0001 ara>
 qSOFA rec 1 vs 0 2.28 (1.53,3.38)  < 0.0001 1.81 (1.09,2.98) 0.0213
 qSOFA rec 2 vs 0 6.83 (4.13,11.28)  < 0.0001 5.16 (3.07,8.66)  < 0.0001
 qSOFA rec 3 vs 0 8.21 (5.64,11.95)  < 0.0001 11.81 (6.46,21.57)  < 0.0001
Creatinine ≥ 1.5 mg/dL 2.02 (1.39,2.94) 0.0002 2.16 (1.39,3.34) 0.0006
  1. Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
  2. MV mechanical ventilation; NMV non mechanical ventilation; HR hazard ratio; CI confidence interval