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Table 3 Univariable and multivariable analysis of in-hospital survival in admitted COVID-19 white patients (n = 338)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Variable/Category

Univariate analysis

Multivariable analysis

HR (95% CI)

P value

HR (95% CI)

P value

MP dose

 

< 0.0001

 

 < 0.0001

 LD MP vs NMP

0.35 (0.22,0.56)

 < 0.0001

0.37 (0.23,0.59)

< 0.0001

 HD MP vs NMP

0.55 (0.34,0.88)

0.0132

0.56 (0.35,0.91)

0.0183

 HD MP vs LD MP

1.56 (0.94,2.57)

0.0855

1.53 (0.91, 2.56)

0.1076

Diabetes

1.05 (0.72,1.51)

0.8124

  

Hypertension

2.03 (1.36,3.05)

0.0006

  

Chronic kidney disease

1.66 (1.01,2.73)

0.0468

  

Male vs female

1.38 (0.94,2.03)

0.1050

  

Respiratory rate > 22 bpm

1.66 (1.07,2.57)

0.0232

  

Older age ≥ 60 years

2.22 (1.31,3.75)

0.0030

  

Obesity status BMI ≥ 30 kg/m2

1.05 (0.73,1.51)

0.8053

  

Cancer

1.90 (1.24,2.92)

0.0032

1.68 (1.03,2.69)

0.0376

CRP > 20 mg/L

0.77 (0.45,1.33)

0.3500

  

Ferritin ≥ 1400 μg/L

1.11 (0.74,1.67)

0.6028

  

Supplemental oxygen

 

0.0593

  

 NMV vs none

1.33 (0.72,2.47)

0.3661

  

 MV vs none

1.72 (1.09,2.71)

0.0194

  

qSOFA

 

 < 0.0001

 

 < 0.0001 ara>

 qSOFA rec 1 vs 0

2.28 (1.53,3.38)

 < 0.0001

1.81 (1.09,2.98)

0.0213

 qSOFA rec 2 vs 0

6.83 (4.13,11.28)

 < 0.0001

5.16 (3.07,8.66)

 < 0.0001

 qSOFA rec 3 vs 0

8.21 (5.64,11.95)

 < 0.0001

11.81 (6.46,21.57)

 < 0.0001

Creatinine ≥ 1.5 mg/dL

2.02 (1.39,2.94)

0.0002

2.16 (1.39,3.34)

0.0006

  1. Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
  2. MV mechanical ventilation; NMV non mechanical ventilation; HR hazard ratio; CI confidence interval
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BMC Infectious Diseases

ISSN: 1471-2334

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