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Table 2 Univariable and multivariate analysis of in-hospital survival in admitted COVID-19 Black patients (n = 102)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Variable/Category Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
MP dose   0.1110   
 LD MP vs NMP 0.59 (0.24,1.43) 0.2399   
 HD MP vs NMP 1.48 (0.60,3.66) 0.3916   
 HD MP vs LD MP 2.53 (1.06,6.06) 0.0369   
Diabetes 1.03 (0.50,2.14) 0.9348   
Hypertension 0.87 (0.36,2.10) 0.7564   
Chronic kidney disease 0.79 (0.18,3.60) 0.7653   
Male vs female 0.97 (0.47,2.01) 0.9417   
Respiratory rate > 22 bpm 1.96 (0.87,4.40) 0.1031   
Older age ≥ 60 years 4.11 (1.31,12.90) 0.0152 3.71 (1.15,11.95) 0.0281
Obesity status BMI ≥ 30 kg/m2 0.51 (0.23,1.11) 0.0907   
Cancer 2.28 (0.49,10.66) 0.2953   
CRP > 20 mg/L 1.45 (0.58,3.61) 0.4221   
Ferritin ≥ 1400 μg/L 1.14 (0.45,2.86) 0.7848   
Supplemental oxygen   0.0370   0.0208
 NMV vs none 2.18 (0.52,9.12) 0.2839 2.63 (0.58,11.93) 0.2088
 MV vs none 4.36 (1.29,14.76) 0.0180 5.07 (1.42,18.07) 0.0123
qSOFA    < 0.0001   
 qSOFA 1 vs 0 1.77 (0.64,4.92) 0.2738   
 qSOFA 2 vs 0 2.61 (1.16,5.89) 0.0209   
 qSOFA 3 vs 0 21.33 (8.84,51.44)  < 0.0001   
Creatinine ≥ 1.5 mg/dL 3.59 (1.61,8.02) 0.0018 3.61 (1.71,7.59) 0.0007
  1. Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
  2. MV mechanical ventilation; NMV non-mechanical ventilation; HR hazard ratio; CI confidence interval