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Table 2 Univariable and multivariate analysis of in-hospital survival in admitted COVID-19 Black patients (n = 102)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Variable/Category

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

MP dose

 

0.1110

  

 LD MP vs NMP

0.59 (0.24,1.43)

0.2399

  

 HD MP vs NMP

1.48 (0.60,3.66)

0.3916

  

 HD MP vs LD MP

2.53 (1.06,6.06)

0.0369

  

Diabetes

1.03 (0.50,2.14)

0.9348

  

Hypertension

0.87 (0.36,2.10)

0.7564

  

Chronic kidney disease

0.79 (0.18,3.60)

0.7653

  

Male vs female

0.97 (0.47,2.01)

0.9417

  

Respiratory rate > 22 bpm

1.96 (0.87,4.40)

0.1031

  

Older age ≥ 60 years

4.11 (1.31,12.90)

0.0152

3.71 (1.15,11.95)

0.0281

Obesity status BMI ≥ 30 kg/m2

0.51 (0.23,1.11)

0.0907

  

Cancer

2.28 (0.49,10.66)

0.2953

  

CRP > 20 mg/L

1.45 (0.58,3.61)

0.4221

  

Ferritin ≥ 1400 μg/L

1.14 (0.45,2.86)

0.7848

  

Supplemental oxygen

 

0.0370

 

0.0208

 NMV vs none

2.18 (0.52,9.12)

0.2839

2.63 (0.58,11.93)

0.2088

 MV vs none

4.36 (1.29,14.76)

0.0180

5.07 (1.42,18.07)

0.0123

qSOFA

 

 < 0.0001

  

 qSOFA 1 vs 0

1.77 (0.64,4.92)

0.2738

  

 qSOFA 2 vs 0

2.61 (1.16,5.89)

0.0209

  

 qSOFA 3 vs 0

21.33 (8.84,51.44)

 < 0.0001

  

Creatinine ≥ 1.5 mg/dL

3.59 (1.61,8.02)

0.0018

3.61 (1.71,7.59)

0.0007

  1. Risk of in-hospital mortality by Cox regression model. Any P < 0.05 was statistically significant
  2. MV mechanical ventilation; NMV non-mechanical ventilation; HR hazard ratio; CI confidence interval
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BMC Infectious Diseases

ISSN: 1471-2334

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