Table 2 Factors associated with survival in patients with AIDS followed for up to 10 years after diagnosis, São Paulo State, 2003 to 2014
Characteristics | Total (n = 35,515) | Dead (n = 8,486) | Alive (n = 27,029) | HRunadjusted (95% CI) | HRadjusted (95% CI) |
|---|---|---|---|---|---|
N (%) | N (%) | N (%) | |||
Sex | |||||
Female | 13,148 (100.0) | 2686 (20.4) | 10,462 (79.6) | 1 | 1 |
Male | 22,367 (100.0) | 5800 (25.9) | 16,567 (74.1) | 1.37 (1.31–1.45) | 1.26 (1.14–1.39) |
Age group (years) | |||||
13 to 29 | 8202 (100.0) | 1584 (19.3) | 6618 (80.7) | 1 | 1 |
30 to 49 | 22,963 (100.0) | 5564 (24.2) | 17,399 (75.8) | 1.36 (1.28–1.45) | 1.14 (1.04–1.26) |
≥ 50 | 4350 (100.0) | 1338 (30.8) | 3012 (69.2) | 1.94 (1.79–2.11) | 1.35 (1.18–1.54) |
Year of AIDS diagnosis | |||||
2007 | 6178 (100.0) | 1202 (19.5) | 4976 (80.5) | 1 | 1 |
2006 | 6506 (100.0) | 1394 (21.4) | 5112 (78.6) | 1.01 (1.01–1.10) | 1.02 (1.01–1.02) |
2005 | 7097 (100.0) | 1710 (24.1) | 5387 (75.9) | 1.06 (1.01–1.18) | 1.03 (1.03–1.04) |
2004 | 7220 (100.0) | 1846 (25.6) | 5374 (74.4) | 1.09 (1.01–1.18) | 1.05 (1.04–1.06) |
2003 | 8514 (100.0) | 2334 (27.4) | 6180 (72.6) | 1.13 (1.04–1.22) | 1.10 (1.05–1.12) |
Region* | |||||
GSPRa | 5586 (100.0) | 1252 (22.4) | 4334 (77.6) | 1 | 1 |
SPC | 12,880 (100.0) | 2994 (23.2) | 9886 (76.8) | 1.05 (1.02–1.12) | 1.16 (1.01–1.32) |
ISPS | 14,958 (100.0) | 3752 (25.1) | 11,206 (74.9) | 1.14 (1.04–1.16) | 1.43 (1.25–1.62) |
SPCA | 2085 (100.0) | 487 (23.4) | 1598 (76.6) | 1.33 (1.09–1.42) | 1.49 (1.21–1.82) |
Education (years of schooling) | |||||
≥ 12 | 3065 (100.0) | 432 (14.1) | 2633 (85.9) | 1 | 1 |
8 to 11 | 10,643 (100.0) | 1980 (18.6) | 8663 (81.4) | 1.36 (1.22–1.51) | 1.64 (1.35–1.99) |
4 to 7 | 11,065 (100.0) | 2929 (26.5) | 8136 (73.5) | 2.02 (1.82–2.23) | 2.35 (1.93–2.86) |
1 to 3 | 3513 (100.0) | 1086 (30.9) | 2427 (69.1) | 2.38 (2.02–2.81) | 2.41 (1.77–3.30) |
Illiterate | 683 (100.0) | 209 (30.6) | 474 (69.4) | 2.42 (2.17–2.71) | 2.61 (2.11–3.24) |
Race | |||||
White | 19,412 (100.0) | 4538 (23.4) | 14,874 (76.6) | 1 | 1 |
Mixed race/black | 7428 (100.0) | 1706 (23.0) | 5722 (77.0) | 1.29 (1.19–1.40) | 1.07 (1.02–1.18) |
Black | 3125 (100.0) | 916 (29.3) | 2209 (70.7) | 2.11 (1.22–3.64) | 1.27 (1.12–1.45) |
Yellow | 147 (100.0) | 38 (25.9) | 109 (74.1) | 1.27 (0.90–1.80) | 0.47 (0.17–1.25) |
Indigenous | 40 (100.0) | 14 (35.0) | 26 (65.0) | 0.96 (0.90–1.02) | 1.67 (0.54–5.21) |
Exposure category | |||||
MSM | 7160 (100.0) | 1203 (16.8) | 5957 (83.2) | 1 | 1 |
Heterosexual | 20,978 (100.0) | 4427 (21.1) | 16,551 (78.9) | 1.30 (1.21–1.39) | 1.16 (1.03–1.31) |
IDU | 3539 (100.0) | 1203 (34.0) | 2336 (66.0) | 2.35 (2.15–2.58) | 1.73 (1.49–2.02) |
TB–HIV co-infection | |||||
No | 30,934 (100.0) | 6712 (21.7) | 24,222 (78.3) | 1 | 1 |
Yes | 4581 (100.0) | 1774 (38.7) | 2807 (61.3) | 2.05 (1.94–2.16) | 1.70 (1.49–1.87) |
ARV regimenb | |||||
HAART2 | 1226 (100.0) | 82 (6.7) | 1144 (93.3) | 1 | 1 |
HAART1 | 24,188 (100.0) | 2593 (10.7) | 21,595 (89.3) | 1.71 (1.37–2.13) | 1.94 (1.47–2.55) |
Pre-HAART | 28 (100.0) | 5 (17.9) | 23 (82.1) | 3.07 (1.25–7.58) | 5.35 (4.03–7.10) |
No ARV | 10,073 (100.0) | 5806 (57.6) | 4267 (42.4) | 17.6 (14.2–21.9) | 8.22 (2.95–22.87) |
CD4 (cells/mm3) | |||||
≥ 500 | 3896 (100.0) | 294 (7.5) | 3602 (92.5) | 1 | 1 |
350–499 | 3533 (100.0) | 331 (9.4) | 3202 (90.6) | 1.26 (1.05–1.50) | 1.31 (1.07–1.60) |
200–349 | 11,198 (100.0) | 1263 (11.3) | 9935 (88.7) | 1.65 (1.43–1.89) | 1.47 (1.25–1.74) |
< 200 | 11,228 (100.0) | 2000 (17.8) | 9228 (82.2) | 2.78 (2.43–3.18) | 2.31 (1.97–2.72) |
Viral load | |||||
40–500 | 3978 (100.0) | 327 (8.2) | 3651 (91.8) | 1 | 1 |
> 500 | 23,381 (100.0) | 3281 (14.0) | 20,100 (86.0) | 1.91 (1.68–2.17) | 1.99 (1.72–2.30) |