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Table 2 The clinical characteristics of patients with different disease severity

From: Human rhinoviruses prevailed among children in the setting of wearing face masks in Shanghai, 2020

 

URTI (n = 72)

Non-severe LRTI (n = 285)

Severe LRTI (n = 31)

p-value

Male

42 (58.3%)

170 (59.6%)

11 (35.5%)

0.0350*

Age, median (min–max)

1y9m (5d to 14y)

7m5d (1d to 17y)

1y6m (3m27d to 7y)

0.1427

Hospital stays, median (min–max), days

–

9 (1–104)

19 (4–120)

0.0007*

Symptom

 Fever

29 (40.3%)

61 (21.4%)

6 (19.4%)

0.0031*

 Cough

12 (16.7%)

112 (39.3%)

18 (58.1%)

< 0.0001*

 Wheeze

5 (6.9%)

34 (11.9%)

7 (22.6%)

0.0790

 Tachypnea

0

9 (3.2%)

10 (32.3%)

< 0.0001*

 Cyanosisa

0

0

7 (22.5%)

< 0.0001*

 Unable to drink/breastfeeda

0

0

1 (3.2%)

0.0031*

 Respiratory failurea

0

0

17 (54.8%)

< 0.0001*

 Seizurea

0

0

5 (16.1%)

< 0.0001*

 Lethargic/unconsciousa

0

0

2 (6.5%)

< 0.0001*

 Apneaa

0

0

1 (3.2%)

0.0031*

Underlying disease

24 (33.3%)

178 (62.4%)

27 (87.1%)

< 0.0001*

 Cardiovascular system

2 (2.8%)

44 (15.4%)

8 (25.8%)

–

 Hepatobiliary system

1 (1.4%)

42 (14.7%)

3 (9.7%)

–

 Immune deficiency

3 (4.2%)

6 (2.1%)

2 (6.5%)

–

 Hemopoietic system

4 (5.6%)

3 (1.1%)

1 (3.2%)

–

Co-infection

–

42 (14.7%)

4 (12.9%)

0.9946

 Virus

–

12 (4.2%)

2 (6.5%)

–

 Bacteria

–

19 (6.7%)

3 (9.7%)

–

 Fungi

–

4 (1.4%)

2 (6.5%)

–

 Mycoplasma

–

8 (2.8%)

0

–

  1. URTI upper respiratory infection, LRTI lower respiratory infection
  2. *P < 0.05 was considered of significant difference among the three groups
  3. aThese symptoms were included in the criteria of severe LRTI cases