| n | GBP5+ | IGRA+ | P value |
---|
Active TB | 232 | 181 (78.02%) | 180 (77.59%) | >0.999 |
PTB | 204 | 158 (77.45%) | 160 (78.43%) | 0.905 |
EPTB | 28 | 23 (82.14%) | 20 (71.43%) | 0.528 |
non–TB | 238 | 79 (33.19%) | 56 (23.53%) | 0.025 |
NTM | 11 | 8 (72.73%) | 2 (18.18%) | 0.030 |
OLD* | 227 | 71 (31.28%) | 54 (23.79%) | 0.093 |
- The sensitivity, specificity, positive predictive value, and negative predictive value of the GBP5 assay were 78.02, 66.81, 69.61 and 75.71%, respectively, and those of IGRA were 77.59, 76.47%, 76.27 and 77.78%
- GBP5+ Individual with positive GBP5 result, IGRA+Â Individual with positive interferon gamma release assay result, Active TBÂ active tuberculosis, PTBÂ pulmonary tuberculosis, EPTBÂ extrapulmonary tuberculosis, non-TBÂ non-tuberculosis other lung diseases, NTMÂ non-tuberculosis mycobacterium, OLDÂ other lung disease
- *Including fungal pneumonia (n = 7), mycoplasma pneumonia (n = 3), bacterial pneumonia (n = 173), lung cancer (n = 16) and non-infection non-cancer lung disease (n = 28)