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Table 3 Patients’ management at the emergency department and outcomes according to the clinical presentation of sepsis

From: Septic patients without obvious signs of infection at baseline are more likely to die in the ICU

Total, n = 348

Explicit n = 245

Vague n = 103

p

Sepsis management

 ED wait, mean minutes (SD)

27 (47)

11 (50)

0.82

 Sepsis diagnosis upon the ED (%)

211 (86.1)

64 (62.1)

 < 0.001

 Time to sepsis diagnosis, median hours (IQR)

3 (4)

6 (14)

 < 0.001

 Time to antibiotics, median hours (IQR)

4 (4)

7 (20)

 < 0.001

 Time to ICU admission, median hours (IQR)

7 (11)

19 (40)

 < 0.001

 Direct ICU hospitalisation (%)

192 (78.4)

48 (46.6)

 < 0.001

 Appropriate antibiotics (%)

131 (53.5)

46 (44.6)

0.13

Outcomes

 28-day Mortality (%)

66 (26.9)

42 (40.8)

0.011

 In-hospital Mortality (%)

69 (28.2)

47 (45.6)

0.002

 ICU LOS, median days (IQR)

3 (5)

4 (5)

0.24

 Overall LOS, median days (IQR)

13 (15)

11 (17)

0.63

  1. ICU, Intensive Care Unit; ARDS, Acute Respiratory Distress Syndrome; GCS, Glasgow Coma Score; LOS, Length of Stay; IQR, Inter Quartile Range