Variable | Cured No. (%) | Univariate analysis OR (95%CI) | p-value | Multivariate analysis OR (95%CI) | p-value |
---|---|---|---|---|---|
Gender | Â | Â | Â | Â | Â |
 Female  Male | 73 (43.5) 73 (39) | Referent 0.833 (0.546–1.273) | 0.399 |  |  |
Age (years) | Â | Â | Â | Â | Â |
 ≤ 40  > 40 | 112 (43.6) 34 (34.7) | Referent 0.688 (0.424–1.115) | 0.129 | Referent 0.990 (0.488–2.009) | 0.979 |
Baseline body weight (kg) | Â | Â | Â | Â | Â |
 < 40  ≥ 40 | 42 (33.9) 104 (45) | Referent 1.599 (1.016–2.516) | 0.042 | Referent 1.661 (0.922–2.994) | 0.091 |
Marital status | Â | Â | Â | Â | Â |
 Single  Married  Widow | 54 (47.4) 90 (38.6) 2 (25) | Referent 0.699 (0.445–1.099) 0.370 (0.072–1.913) | 0.121 0.236 | Referent 0.737 (0.394–1.378) 0.396 (0.045–3.484) | 0.339 0.404 |
History of TB treatment | Â | Â | Â | Â | Â |
 No  Yes | 14 (58.3) 132 (39.9) | Referent 0.474 (0.204–1.098) | 0.082 | Referent 0.527 (0.186–1.492) | 0.228 |
History of MDR-TB treatment | Â | Â | Â | Â | Â |
 No  Yes | 97 (42.2) 49 (39.2) | Referent 0.884 (0.567–1.379) | 0.587 |  |  |
Baseline sputum smear grading | Â | Â | Â | Â | Â |
 Negative  Scanty* + 1† + 2‡ + 3§  Not available | 27 (48.2) 51 (46.4) 67 (75.7) 1 (20) | Referent 0.928 (0.487–1.768) 0.615 (0.336–1.125) 0.269 (0.028–2.558) | 0.821 0.115 0.253 | Referent 1.144 (0.491–2.665) 0.603 (0.276–1.318) 0.709 (0.061–8.238) | 0.756 0.205 0.783 |
Co-morbidity | Â | Â | Â | Â | Â |
 No  Yes | 120 (40.1) 26 (46.4) | Referent 1.293 (0.728–2.295) | 0.380 |  |  |
Number of resistant drugs | Â | Â | Â | Â | Â |
 4–6  7–8  > 8 | 46 (46) 54 (32.5) 46 (51.7) | Referent 0.566 (0.340–0.943) 1.256 (0.709–2.226) | 0.029 0.435 | Referent 0.523 (0.257–1.066) 1.010 (0.365–2.791) | 0.075 0.985 |
Resistance to all five FLD | Â | Â | Â | Â | Â |
 No  Yes | 79 (37.3) 67 (46.9) | Referent 1.484 (0.965–2.283) | 0.072 | Referent 1.798 (0.760–2.674) | 0.058 |
Resistance to ethambutol | Â | Â | Â | Â | Â |
 No  Yes | 39 (42.4) 107 (40.7) | Referent 0.932 (0.576–1.508) | 0.775 |  |  |
Resistance to pyrazinamide | Â | Â | Â | Â | Â |
 No  Yes | 43 (41) 103 (41.2) | Referent 1.010 (0.536–1.606) | 0.965 |  |  |
Resistance to streptomycin | Â | Â | Â | Â | Â |
 No  Yes | 53 (37.9) 93 (43.3) | Referent 1.251 (0.810–1.934) | 0.313 |  |  |
Resistance to ethionamide | Â | Â | Â | Â | Â |
 No  Yes | 127 (41) 19 (42.2) | Referent 1.053 (0.559–1.984) | 0.873 |  |  |
Resistance to SLIs | Â | Â | Â | Â | Â |
 No  Yes | 85 (43.4) 61 (38.4) | Referent 0.813 (0.531–1.245) | 0.341 |  |  |
Use of moxifloxacin | Â | Â | Â | Â | Â |
 No  Yes | 46 (39.0) 100 (42.2) | Referent 1.142 (0.728–1.793) | 0.563 |  |  |
Use of para-amino salicylic acid | Â | Â | Â | Â | Â |
 No  Yes | 11(27.5) 135 (42.9) | Referent 1.977 (0.954–4.099) | 0.067 | Referent 1.539 (0.620–3.823) | 0.330 |
Use of clarithromycin | Â | Â | Â | Â | Â |
 No  Yes | 64 (43.8) 82 (39.2) | Referent 0.827 (0.539–1.270) | 0.386 |  |  |
Use of co-amoxiclav | Â | Â | Â | Â | Â |
 No  Yes | 47 (39.5) 99 (41.9) | Referent 1.107 (0.706–1.735) | 0.657 |  |  |
Use of bedaquiline | Â | Â | Â | Â | Â |
 No  Yes | 135 (41.9) 11 (33.3) | Referent 0.693 (0.325–1.476) | 0.342 |  |  |
Use of clofazimine | Â | Â | Â | Â | Â |
 No  Yes | 71 (43.3) 75 (39.3) | Referent 0.847 (0.554–1.294) | 0.442 |  |  |
Use of linezolid | Â | Â | Â | Â | Â |
 No  Yes | 43 (45.7) 103 (42.2) | Referent 1.155 (0.730–1.827) | 0.538 |  |  |
Use of amikacin | Â | Â | Â | Â | Â |
 No  Yes | 117 (41.2) 29 (40.8) | Referent 0.986 (0.581–1.673) | 0.957 |  |  |
Use of capreomycin | Â | Â | Â | Â | Â |
 No  Yes | 38 ( 40.4) 108 (41.4) | Referent 1.040 (0.644–1.681) | 0.872 |  |  |
Use of high dose isoniazid | Â | Â | Â | Â | Â |
 No  Yes | 138 (43.1) 8 (22.9) | Referent 0.391 (0.172–0.887) | 0.025 | Referent 0.433 (0.57–1.195) | 0.106 |
Use of ethambutol | Â | Â | Â | Â | Â |
 No  Yes | 118 (40.7) 28 (43.1) | Referent 1.103 (0.640–1.900) | 0.724 |  |  |
SCC at month 2 | Â | Â | Â | Â | Â |
 No  Yes | 85 (32.9) 61 (62.9) | Referent 3.449 (2.119–5.612) |  < 0.001 | Referent 0.658 (0.310–1.394) | 0.274 |
SCC at month 4 | Â | Â | Â | Â | Â |
 No  Yes | 44 (22) 102 (65.8) | Referent 6.823 (4.259–10.931) |  < 0.001 | Referent 1.037 (0.388–2.773) | 0.942 |
SCC at month 6 | Â | Â | Â | Â | Â |
 No  Yes | 21 (12.7) 125 (66.1) | Referent 12.770 (7.348–21.923) |  < 0.001 | Referent 15.603 (6.168–39.467) |  < 0.001 |