Skip to main content

Table 3 Association between seroconversion and duration of IgG and IgM antibodies against SARS-CoV-2

From: Long-term immune responses in patients with confirmed novel coronavirus disease-2019: a 9-month prospective cohort study in Shanghai, China

 

Generalized log-rank test

Proportional hazards models¶

Time interval#,

Median (IQR)

P value

Hazard ratio (95%CI)

P value

IgG seroconversion

    

 Abroad imported case: yes

27 (19,35)

0.016*

6.331 (1.56–26.63)

0.010*

  No

61 (58,82.5)

   

 Fever: yes

60 (53,77)

0.075

0.450 (0.204–0.993)

0.048*

  No

27.5 (20.5,54.5)

   

IgM seroconversion

    

 Abroad imported case: yes

26.5 (21.5,33)

0.001**

5.152 (1.936–13.711)

0.001**

 No

61 (58,90)

   

Involved in a cluster: yes

61 (59,150)

0.008**

0.365 (0.180–0.743)

0.005**

  No

42 (26,62)

   

 Any symptom: yes

59.5 (32,89)

0.039*

0.368 (0.161–0.842)

0.018*

  No

27.5 (22,53)

   

 Pneumonia: yes

60 (30,90)

0.015*

0.477 (0.261–0.873)

0.016*

  No

53 (26,62)

   

IgM duration#

    

 Age: ≥ 40 years

89 (30,122)

0.004**

0.074 (0.012–0.442)

0.004**

  < 40 years

6 (5,6.5)

   
  1. Each serological result of patients was regarded as interval censored
  2. *P < 0.05; **P < 0.01
  3. ¶Only statistically significant results are shown in the table
  4. #Time interval for seroconversion means the interval from illness onset to first positive test for antibody. Time interval for duration means the interval from first to last positive antibody test