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Table 4 Factors associated with elevated ALT in IM patients (multivariate analysis)

From: Adenosine deaminase as a marker for the severity of infectious mononucleosis secondary to EBV in children

Variable

Model 1

Model 2

Model 3

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Plasma EBV-DNA lg(copies/ml)

2.551 (1.325–4.912)

0.005

2.650 (1.358–5.173)

0.004

1.370 (0.698–2.687)

0.361

ADA(U/L)

1.125 (1.073–1.179)

< 0.01

1.129 (1.075–1.185)

< 0.001

1.124 (1.063–1.189)

< 0.001

IgG(g/L)

1.297 (1.103–1.525)

0.002

1.349 (1.130–1.610)

0.001

1.099 (0.879–1.375)

0.406

CD8+ (%)

1.042 (1.004–1.082)

0.030

1.050 (1.008–1.093)

0.019

0.970 (0.917–1.026)

0.294

  1. ALT, alanine aminotransferase; IM, infectious Mononucleosis; ADA, adenosine deaminase; IgG, immunoglobulin G; OR, odds ratio; CI, confidence interval. Model 1 was not adjusted. Model 2 was adjusted for age and sex. Model 3 was adjusted as Model 2 + Plasma EBV-DNA, ADA, IgG, CD8+ (%)
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BMC Infectious Diseases

ISSN: 1471-2334

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