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Table 1 Comparison of Laboratory Findings between IM group and non-IM group

From: Adenosine deaminase as a marker for the severity of infectious mononucleosis secondary to EBV in children

Parameters

IM group (n = 104)

Non-IM group (n = 50)

P

Sex (male)

47 (45.2)

27 (54.0)

0.306

Age (years)

2.9 (1.9–4.1)

3.2 (2.2–5.1)

0.207

Disease course (days)

3.0 (3.0–4.0)

3.0 (2.8-4.0)

0.263

WBC (×109/L)

16.4 (12.3–21.0)

13.7 (9.3–19.3)

0.049

Lymphocyte count(×109/L)

10.6 (7.0–14.0)

3.4 (2.3–5.2)

< 0.001

ADA (U/L)

51.6 (44.5–66.5)

20.1 (17.1–23.8)

< 0.001

IgA (g/L)

1.4 (1.0–1.9)

0.8 (0.5–1.2)

< 0.001

IgG (g/L)

11.3 ± 2.8

7.7 ± 2.2

< 0.001

IgM (g/L)

1.6 (1.3–2.2)

1.1 (0.8–1.6)

< 0.001

CD3+ (%)

79.1 (72.6–82.8)

63.8 (54.1–71.8)

< 0.001

CD3 + CD4+ (%)

17.6 (13.3–21.7)

32.1 (24.8–39.2)

< 0.001

CD3 + CD8+ (%)

53.9 ± 11.0

25.0 ± 8.0

< 0.001

CD4+/CD8+

0.3 (0.2-0.475)

1.2 (1.0-1.7)

< 0.001

CD3-CD (16 + 56) + (%)

11.9 (8.1–16.9)

11.1 (6.7–16.1)

0.616

CD3-CD19+ (%)

7.8 (5.2–9.8)

20.9 (16.0–29.8)

< 0.001

CD19 + CD23+ (%)

4.0 (2.4–6.3)

9.9 (6.8–12.7)

< 0.001

  1. The data presented as median [interquartile range], mean ± standard deviation and n (%). The univariate analyses were performed using Mann-Whitney U-test for skewed distribution variables, t-test for normal distribution variables and the chi-square test for categorical variables. WBC, white blood cell; ADA, adenosine deaminase; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M