Skip to main content

Table 2 The area under ROC curve and its relevant parameters of liver fibrosis diagnosed by four non-invasive diagnostic indicators single or in combination

From: Assessment of liver fibrosis by transient elastography and multi-parameters model in young children with chronic hepatitis B virus infection

Parameters

n

AUC

P

95% CI

Cut-off

Se (%)

Sp (%)

PPV (%)

NPV (%)

+ LR

− LR

P

X2

APRI

148

0.701

0.001

0.603–0.800

0.50

60.00

78.57

92.30

31.40

2.80

0.51

  

AAR

148

0.440

0.326

0.328–0.552

0.90

35.83

85.71

91.50

23.80

2.51

0.75

  

FIB-4

148

0.651

0.013

0.546–0.755

0.10

65.00

64.29

88.60

30.00

1.82

0.54

  

APRI + FIB-4

148

0.703

0.001

0.605–0.801

0.80

51.67

89.29

95.40

30.10

4.82

0.54

0.560

6.788

LSM

43

0.740

0.028

0.543–0.938

5.9 kPa

94.12

55.56

88.90

71.40

2.12

0.11

  

APRI + LSM

43

0.761

0.017

0.580–0.942

0.57

94.12

55.56

88.90

71.40

2.12

0.11

0.636

6.104

FIB-4 + LSM

43

0.758

0.018

0.555–0.961

0.58

94.12

55.56

88.90

71.40

2.12

0.11

0.384

8.529

LSM + APRI + FIB-4

43

0.771

0.017

0.580–0.942

0.53

97.06

55.56

89.20

83.30

2.18

0.05

0.264

0.170

  1. Compared with APRI, Z = 0.346, P = 0.364 compared with FIB-4, Z = 0.780, P = 0.218; compared with LSM + APRI + FIB-4, Z = 0.225, P = 0.411