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Table 4 Association between high-risk HPV prevalence and selected characteristics among sexually experienced participants, by HIV status

From: HPV prevalence among young adult women living with and without HIV in Botswana for future HPV vaccine impact monitoring

 

HIV-positive participants

N = 265

HIV-negative participants

N = 372

High-risk HPV prevalence

n (%)

Unadjusted

PR (95% CI)

Adjusteda

PR (95% CI)

High-risk HPV prevalence

n (%)

Unadjusted

PR (95% CI)

Adjusteda

PR (95% CI)

Age of first sex (years)

 ≥ 18

162 (78.3)

Ref

 

198 (64.5)

Ref

 

 < 18

45 (77.6)

1.01 (0.86, 1.18)

 

46 (70.8)

0.91 (0.76, 1.09)

 

Age of first sex partner (years)

 ≥ 20

157 (78.9)

Ref

 

153 (65.1)

Ref

 

 < 20

50 (75.8)

1.04 (0.89, 1.22)

 

91 (66.9)

0.97 (0.84, 1.13)

 

Age of current sex partner (years)

 ≥ 24

148 (77.9)

Ref

 

87 (70.7)

Ref

 

 < 24

59 (78.7)

0.99 (0.86, 1.14)

 

157 (63.3)

1.12 (0.96, 1.30)

 

Lifetime no. sex partners

 1–2

68 (70.8)

Ref

Ref

135 (57.9)

Ref

Ref

 ≥ 3

139 (82.3)

1.16 (1.00, 1.34)

1.14 (0.99, 1.32)

109 (78.4)

1.35 (1.18, 1.56)

1.29 (1.12, 1.48)

Condom use in past 3 monthsb

 Sometimes/never

68 (77.3)

Ref

 

134 (74.4)

Ref

Ref

 Always

119 (76.8)

0.99 (0.86, 1.15)

 

99 (59.3)

0.79 (0.68, 0.93)

0.83 (0.71, 0.96)

Ever pregnant

 No

120 (83.9)

Ref

Ref

218 (65.9)

Ref

 

 Yes

87 (71.3)

0.85 (0.74, .97)

0.86 (.76, .98)

26 (63.4)

0.96 (0.75, 1.23)

 

CD4 count (cells/mm3)

 ≤ 350

41 (89.1)

Ref

Ref

   

 > 350

165 (75.7)

0.85 (0.75, 0.96)

0.89 (0.80, 0.99)

   

Viral load (copies/mL)

 > 400

15 (100.0)

    

 ≤ 400

187 (77.0)

    

ART age of initiation (years)

 < 15

46 (74.2)

Ref

    

 ≥ 15

161 (79.3)

1.07 (0.91, 1.26)

    
  1. aUnadjusted prevalence ratios and 95% confidence intervals (CI) were calculated using log-binomial regression to evaluate associations between participant characteristics and any HPV. Multivariable models were developed using backward selection. (p < 0.3 to enter, p < 0.15 to stay) to identify predictors of having a prevalent HPV infection in this population
  2. bData not shown for participants reporting no sex in past 3 months