Table 3 Analysis of risk factors in patients with single candidal infection and multiple candidal infections
|  | Single candidal infection (N = 176) | Multiple candidal infection (n = 70) | Statistic | P value |
|---|---|---|---|---|
Male | 121 (68.75%) | 38 (54.29%) | 4.584 | 0.032 |
Age (years)a | 63.00 (54.00, 74.00) | 65.00 (53.00, 76.50) | − 1.024 | 0.306 |
Length of stay (days)a | 42.00 (28.00, 66.25) | 57.00 (37.50, 97.75) | − 3.338 | < 0.001 |
Length of stay in ICUa | 7.00 (0.00, 20.00) | 22.50 (6.00, 61.75) | − 4.410 | < 0.001 |
Solid tumor | 74 (42.05%) | 22 (31.43%) | 2.372 | 0.124 |
Diabetes | 25 (14.20%) | 22 (31.43%) | 9.613 | 0.002 |
Pancreatitisb | 20 (11.36%) | 5 (7.14%) | 0.977 | 0.323 |
Total parenteral nutrition | 139 (78.98%) | 57 (81.43%) | 0.186 | 0.666 |
Renal failure | 23 (13.07%) | 13 (18.57%) | 1.214 | 0.271 |
Recent surgery (within 2Â weeks) | 91 (51.70%) | 21 (30.00%) | 9.513 | 0.002 |
Use immunosuppressants within the past 30 daysb | 14 (7.95%) | 1 (1.43%) | – | 0.074b |
Stay in ICU during hospitalization | 114 (64.77%) | 54 (77.14%) | 3.539 | 0.060 |
Hypoproteinemia | 125 (71.02%) | 44 (62.86%) | 1.553 | 0.213 |
Invasive mechanical ventilation | 103 (58.52%) | 50 (71.43%) | 3.548 | 0.060 |
Urinary catheter | 146 (82.95%) | 64 (91.43%) | 2.879 | 0.090 |
Gastric tube | 116 (65.91%) | 50 (71.43%) | 0.695 | 0.404 |
Central venous catheter | 127 (72.16%) | 58 (82.86%) | 3.074 | 0.080 |
Drainage catheter | 116 (65.91%) | 52 (74.29%) | 1.623 | 0.203 |
Septic shock | 35 (19.89%) | 23 (32.86%) | 4.676 | 0.031 |
Multiple hospitalizations within 2 years (> 2 times) | 115 (65.34%) | 52 (74.29%) | 1.838 | 0.175 |
Persistent fungal infection | 84 (47.73%) | 54 (77.14%) | 21.671 | < 0.001 |
Serum albumin levela (g/L) | 27.00 (22.70, 30.70) | 28.2 (24.18, 31.90) | − 1.579 | 0.114 |
Serum creatinine levela (μmol/L) | 60.00 (43.00,88.00) | 58.00 (35.25, 91.50) | 1.007 | 0.314 |
Leukocyte counta (109/L) | 8.32 (5.69, 11.60) | 8.45 (6.00, 10.91) | − 0.245 | 0.806 |
Total bilirubin levela (μmol/L) | 15.40 (9.50, 31.13) | 13.50 (9.53, 26.05) | 1.261 | 0.207 |
Neutrophil counta (109/L) | 6.68 (4.42, 9.96) | 6.43 (4.36, 8.43) | 0.599 | 0.549 |
Lymphocyte counta (109/L) | 0.75 (0.53, 1.10) | 1.02 (0.75, 1.32) | − 3.127 | 0.002 |
CRPa (mg/mL) | 110.00 (70.83, 169.25) | 93.1 (34.93, 124.50) | 2.196 | 0.028 |
PCTa (ng/mL) | 0.86 (0.27, 4.49) | 0.44 (0.25, 1.19) | 2.257 | 0.024 |