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Table 3 DOT and LOT by pre eMeds and post eMeds for top 5 most commonly used antimicrobials

From: “Antibiotic hardstop” on electronic prescribing: impact on antimicrobial stewardship initiatives in patients with community acquired pneumonia (CAP) and infective exacerbations of chronic obstructive pulmonary disease (IECOPD)

Antibiotic

Pre eMeds

Post eMeds

 

Patients prescribed antibiotic

DOT (days)—mean

Patients prescribed antibiotic

DOT (days)—mean

Pre eMeds vs Post eMeds

Ceftriaxone

74

15.27

85

11.46

p = 0.009*

Doxycycline

57

17.05

49

12.14

p = 0.009*

Azithromycin

30

14.97

37

11.65

p = 0.130

Amoxicillin-Clavulanate

31

18.55

15

17.40

p = 0.763

Piperacillin-Tazobactam

32

15.906

8

12.625

p = 0.528

Antibiotic

Pre eMeds

Post eMeds

 

Patients prescribed antibiotic

LOT (days)—mean

Patients prescribed antibiotic

LOT (days)—mean

Pre eMeds vs Post eMeds

Ceftriaxone

74

8.77

85

6.54

p = 0.006*

Doxycycline

57

9.16

49

6.63

p = 0.021*

Azithromycin

30

8.23

37

6.78

p = 0.211

Amoxicillin-Clavulanate

31

10.77

15

10.73

p = 0.986

Piperacillin-Tazobactam

32

10.41

8

8.25

p = 0.498

  1. P-value calculated using two-sample t-test for continuous variables
  2. *statistically significant p-value (p ≤ 0.05)