Table 3 Clinical characteristics and analysed variables between cases (patients with positive T2Dx results) and matched patients (comparators)
Variables | T2-positive group (n = 18) | Standard blood culture (n = 36) | p value |
|---|---|---|---|
Demographic information | |||
Age (years), mean (SD) | 59.7 (21.1) | 60.2 (16.0) | 0.923 |
Male gender | 13 (72.2) | 24 (66.6) | 0.678 |
Patient’s co-morbidities | |||
Chronic kidney disease | 3 (16.6) | 7 (19.4) | 0.804 |
Hypertension | 9 (50.0) | 12 (33.3) | 0.236 |
Diabetes | 3 (16.6) | 6 (16.6) | 1.000 |
Ischaemic heart disease | 4 (22.2) | 8 (22.2) | 1.000 |
Neurological disease | 4 (22.2) | 4 (11.1) | 0.278 |
COPD | 1 (5.5) | 7 (19.4) | 0.175 |
Obesity | 1 (5.5) | 6 (16.6) | 0.251 |
Cancer (all) | 6 (33.3) | 12 (33.3) | 1.000 |
Solid cancer | 4 (22.2) | 8 (22.2) | 1.000 |
Haematological cancer | 2 (11.1) | 5 (13.8) | 0.774 |
Hospitalisation area | |||
Intensive care unit | 11 (61.1) | 20 (55.5) | 0.697 |
Medical unit | 5 (27.7) | 11 (30.5) | 0.833 |
Surgical unit | 2 (11.1) | 5 (13.8) | 0.774 |
Microorganism | |||
Escherichia coli | 4 (22.2) | 10 (27.7) | 0.660 |
Klebsiella pneumoniae | 4 (22.2) | 9 (25.0) | 0.821 |
Pseudomonas aeruginosa | 2 (11.1) | 4 (11.1) | 1.000 |
Acinetobacter baumannii | 6 (33.3) | 11 (30.5) | 0.835 |
Enterococcus faecium | 2 (11.1) | 4 (11.1) | 1.000 |
Candida spp. | 5 (27.7) | 5 (13.8) | 0.215 |
Mixed species | 5 (27.7) | 6 (16.6) | 0.339 |
Primary site of BSI | |||
Respiratory | 8 (44.4) | 16 (44.4) | 1.000 |
Urinary | 3 (16.6) | 4 (11.1) | 0.566 |
Abdominal | 4 (22.2) | 8 (22.2) | 1.000 |
Heart | 0 | 1 (2.7) | 0.475 |
Skin and soft tissue | 2 (11.1) | 3 (8.3) | 0.739 |
Unknown | 1 (5.5) | 5 (13.8) | 0.358 |
Hospitalisation data | |||
Length of hospitalisation (days), mean (SD) | 32.7 (14.9) | 25.1 (17.5) | 0.115 |
Time from admission to infection (days), mean (SD) | 16.1 (15.7) | 12.3 (15.5) | 0.411 |
Time from infection to discharge/death (days), mean (SD) | 16.8 (11.1) | 12.8 (11.1) | 0.219 |
Miscellaneous | |||
PCT at baseline, mean (SD) | 18.6 (42.8) | 20.6 (37.2) | 0.858 |
Mechanical ventilation | 10 (55.5) | 17 (47.2) | 0.563 |
Inotrope drugs | 9 (50) | 17 (47.2) | 0.847 |
ECMO | 4 (22.2) | 4 (11.1) | 0.278 |
CVVH | 2 (11.1) | 7 (19.4) | 0.438 |
Inappropriate empiric antibiotic therapy | 1 (5.5) | 14 (38.8) | 0.009 |
21-day mortality | 4 (22.2) | 16 (44.4) | 0.110 |