Table 1 Basic characteristics and quality evaluation of the included studies
Author | Year | Country | Type of study | Sex (M/F) | Ages | Sample sizes | Interventions | NOS/Jadad Scores |
|---|---|---|---|---|---|---|---|---|
Leonardo Calza [26] | 2019 | Italy | Cohort study | 138/58 | 43.1 ± 15.2 | 196 | RAL | 6 |
|  |  |  |  | 115/59 | 41.6 ± 12.8 | 174 | DTG | |
|  |  |  |  | 109/49 | 42.5 ± 13.6 | 158 | EVG | |
Peter [27] | 2020 | USA | Cohort study | 917/164 | 44(33–52) | 1081 | RAL | 7 |
|  |  |  |  | 2058/257 | 34(27–45) | 2315 | EVG | |
|  |  |  |  | 1044/166 | 35(28–48) | 1210 | DTG | |
Kassem Bourgi [28] | 2020 | USA | Cohort study | NA | NA | 63 | RAL | 5 |
| Â | Â | Â | Â | NA | NA | 153 | EVG | |
| Â | Â | Â | Â | NA | NA | 135 | DTG | |
Kassem Bourgi [13] | 2020 | USA | Cohort study | 1016/176 | NA | 1192 | RAL | 7 |
| Â | Â | Â | Â | 795/131 | NA | 926 | DTG | |
| Â | Â | Â | Â | 1842/226 | NA | 2068 | EVG | |
Sax [14] | 2020 | USA | RCT | 565/74 | 37 ± 11.9 | 639 | DTG | 4 |
|  |  |  |  | 434/67 | 38 ± 9.5 | 501 | BIC | |
|  |  |  |  | 567/62 | 34 ± 10.8 | 629 | EVG | |
David A Wohl [29] | 2019 | USA | RCT | 282/33 | 35(26–40) | 315 | DTG | 4 |
|  |  |  |  | 285/29 | 31(25–41) | 314 | BIC | |
Stellbrink [30] | 2019 | Germany | RCT | 280/40 | 33(27–46) | 320 | BIC | 6 |
|  |  |  |  | 288/37 | 34(27–46) | 325 | DTG | |
Lake [31] | 2020 | USA | Cohort study | NA | NA | 198 | DTG | 5 |
| Â | Â | Â | Â | NA | NA | 204 | EVG | |
| Â | Â | Â | Â | NA | NA | 289 | RAL |