Table 1 Demographic data, clinical characteristics
Variables | Overall (n = 874) | Non-ESBL-E (n = 602) | ESBL-E (n = 272) | P value |
|---|---|---|---|---|
Gender, n (%) | 0.050 | |||
Male | 236 (27.0) | 145 (24.1) | 91 (33.5) | |
Female | 638 (73.0) | 457 (75.9) | 181 (66.5) | |
Age (years), [median (IQR)] | 62.0 (50–75) | 61 (49–74) | 65.5(52–76) | < 0.001 |
Comorbidity diseases | ||||
Diabetes mellitus, n (%) | 0.038 | |||
Yes | 287 (32.8) | 211 (35.0) | 76 (27.9) | |
No | 587 (67.2) | 391 (65.0) | 196 (72.1) | |
Chronic renal failure, n (%) | 0.208 | |||
Yes | 123 (14.1) | 91 (15.1) | 32 (11.8) | |
No | 751 (85.9) | 511 (84.9) | 240 (88.2) | |
Immunodeficiency, n (%) | 0.056 | |||
Yes | 51 (5.8) | 29 (4.8) | 22 (8.1) | |
No | 823 (94.2) | 573 (95.2) | 250 (91.9) | |
Neoplasia, n (%) | 0.072 | |||
Yes | 103 (11.8) | 63 (10.5) | 40 (14.7) | |
No | 771 (88.2) | 539 (89.5) | 232 (85.3) | |
Recurrent Urinary tract infections, n (%) | < 0.001 | |||
Yes | 134 (15.3) | 66 (11.0) | 68 (25.0) | |
No | 740 (84.7) | 536 (89.0) | 204 (75.0) | |
Severe underlying disease, n (%) | 0.009 | |||
Yes | 66 (7.6) | 36 (6.0) | 30 (11.0) | |
No | 808 (92.4) | 566 (94.0) | 242 (89.0) | |
Hospital stays in preceding 3 months, n (%) | < 0.001 | |||
Yes | 309 (35.4) | 168 (27.9) | 141 (51.8) | |
No | 565 (64.6) | 434 (72.1) | 131 (48.2) | |
Previous hospitalization department | ||||
Medical department, n (%) | 0.005 | |||
Yes | 265 (30.3) | 165 (27.4) | 100 (36.8) | |
No | 609 (69.7) | 437 (72.6) | 172 (63.2) | |
Surgical department, n (%) | < 0.001 | |||
Yes | 174 (19.9) | 99 (16.4) | 75 (27.6) | |
No | 700 (80.1) | 503 (83.6) | 197 (72.4) | |
Intensive Care Unit (ICU), n (%) | 0.047 | |||
Yes | 10 (1.1) | 4 (0.7) | 6 (2.2) | |
No | 864 (98.9) | 598 (99.3) | 266 (97.8) | |
Invasive urological procedure, n (%) | < 0.001 | |||
Yes | 269 (30.8) | 150 (24.9) | 119 (43.8) | |
No | 605 (69.2) | 452 (75.1) | 153 (56.3) | |
Antibiotic use in the past 3 months, n (%) | < 0.001 | |||
Yes | 190 (21.7) | 91 (15.1) | 99 (36.4) | |
No | 684 (78.3) | 511 (84.9) | 173 (63.6) | |
Microorganism, n (%) | ||||
Escherichia coli | 739 (84.6) | 540 (89.7) | 199 (73.2) | < 0.001 |
Klebsiella sp. | 135 (15.4) | 62 (10.3) | 73 (26.8) | < 0.001 |
Mortality, n (%) | ||||
Secondary to infection | 6 (0.7) | 4 (0.7) | 2 (0.7) | 0.604 |
Other cause | 7 (0.8) | 3 (0.5) | 4 (1.5) | 0.140 |