Table 1 Characteristics of the included studies
First author (last name) | Publication year | Country | Journal | Database name | Number of subjects | Age (years) Mean (if the mean value is not mentioned in the paper, age range mentioned is recorded instead) | Gene | SNP |
|---|---|---|---|---|---|---|---|---|
Maiti et al. [25] | 2020 | USA | Immunogenetics | 1000 genome project (https://www.internationalgenome.org/) | N/A | N/A | IFIH1 | rs1990760 |
Torre-Fuentes et al. [6] | 2021 | Spain | Journal of Medical Virology | MS family cohort | 120 | N/A | ACE2, TMPRSS2 | rs75603675, rs61735792, rs61735794 |
Gomez et al. [7] | 2021 | Spain | Cytokine | Hospital Univ. Central Asturias, Spain | 311 | 65.23 | IFITM3 | rs12252 (C) |
Zhang et al. [8] | 2020 | China | The Journal of Infectious Diseases | Patients were recruited from Beijing Youan Hospital, Capital Medical University, Beijing, between January 2020 and February 2020 | 80 | 49.5 | IFITM3 | rs12252 (C) |
Hussain et al. [11] | 2020 | Pakistan | Journal of Medical Virology | Ensembl (https://asia.ensembl.org/index.html), Genome Browser12 (https://genome.ucsc.edu/), gnomAD (https://gnomad.broadinstitute.org/) | N/A | N/A | ACE2 | rs7363582, rs143936283 |
Gomez et al. [9] | 2020 | Spain | Elsevier | Hospital Univ. Central Asturias, Spain | 740 | 67.44 | ACE, ACE2 | rs2285666 |
Wang et al. [12] | 2020 | China | Journal of General Virology | dbSNP (https://www.ncbi.nlm.nih.gov/snp/?cmd=search), National Genomics Data Center (https://ngdc.cncb.ac.cn/) | N/A | N/A | ACE2 | rs143936283 rs267606406 rs4646116 |
Fujikura et al. [15] | 2020 | Japan | Journal of clinical pathology | 1000G (https://www.internationalgenome.org/), NHLBI (https://www.nhlbi.nih.gov/), gnomAD, ToMMo (https://www.megabank.tohoku.ac.jp/english/), UK10K (https://www.uk10k.org/) | 669 | N/A | ACE2, TMPRSS2 | N/A |
Yamamoto et al. [16] | 2020 | Japan | Elsevier | High-coverage sequenced data of the phase 3 panel of the international 1000 Genomes Project (1000Genomes) and the Korean Personal Genome Project (KPGP) | N/A | N/A | ACE, ACE2 | N/A |
Sienko et al. [17] | 2020 | Poland | Clinical Interventions in Aging | N/A | 6272 | N/A | ACE2, TMPRSS2, CD147 | N/A |
Paniri et al. [18] | 2021 | Iran | Gene Rep | NCBI, UniProtKB (https://www.uniprot.org/), PANTHER (http://www.pantherdb.org/) | 52,456 | N/A | ACE2 | rs149039346, rs147311723, rs714205, rs1514283, rs4646175, rs3746444, rs113808830, rs3751304 |
Nguyen et al. [10] | 2020 | Vietnam | PLoS One | A hospital in Vietnam | 44 | 15–74 | ACE2 | N/A |
Senapati et al. [19] | 2020 | India | J Ganet | GTEx (https://gtexportal.org/home/), Uniprot | 26 | 60 or more | ACE2, TMPRSS2, CD26 | rs112657409, rs11910678, rs77675406, rs713400, rs13015258 |
Novelli et al. [20] | 2020 | Italy | Human Genomics | GnomAD | 131 | N/A | ACE2 | N/A |
Vargas-Alarcón et al. [21] | 2020 | Mexico | ELSEVIER | dbSNPs, Ensembl Genome Browser, and 1000 Genome Project databases | N/A | N/A | ACE2, TMPRSS2, TMPRSS11A, ELANE, CTSL | rs12329760 |
Benetti et al. [22] | 2020 | Italy | European Journal of Human Genetics | NIG-db, LOVD (https://www.lovd.nl/), gnomAD, | 389 | N/A | ACE2 | rs775181355, rs762890235 |
Strafella et al. [13] | 2020 | Italy | MDPI | Ensembl, 1000 Genomes, GnomAD | 268 | 46 | ACE2 | rs35803318, rs41303171, rs774469453, rs773676270, rs2285666 |
Shikov et al. [23] | 2020 | Russia | Front Genet | gnomAD | 58 | N/A | ACE2 | rs146598386, rs73195521, rs755766792 |
Srivastava et al. [14] | 2020 | India | Front. Genet | 1000 genome project | N/A | N/A | ACE2 | rs2285666 |
Yang et al. [26] | 2020 | Taiwan | PNAS | GISAID, Illumina | 1932 | N/A | N/A | N/A |
Kim et al. [24] | 2020 | South Korea | MDPI | World Health Organization (WHO) COVID-19 dashboard | N/A | N/A | IFITM3, ACE2, TMPRSS2, IL6, LZTFL1 | rs6598045, rs12252, rs34481144, rs6598045ss |