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Table 1 Diphtheria case-fatality ratios by selected characteristics in Sada'a, 2017–2020, Yemen

From: Diphtheria resurgence in Sada'a-Yemen, 2017–2020

Variable Reported cases n = 747 Deaths n = 48 CFR (%) OR (95% CI) P value
Frequency Percent Frequency Percent
Sex
 Male 367 49 18 38 5 Ref  
 Female 380 51 30 63 8 0.6 (0.91–3.09) 0.129
Age groups
 < 5 years 131 18 14 29 11 9.28 (1.2–71.53)  < 0.001
 5–< 10 years 195 26 17 35 9 3.61 (0.47–27.93) 0.322
 10–< 15 years 258 35 11 23 4 2.49 (0.31–19.88) 0.617
 15–< 20 years 45 6 1 2 2 Ref  
 20–< 25 years 32 4 2 4 6 1.28 (0.08–21.15) 1.00
 25–< 30 years 33 4 1 2 3 1.43(0.07–23.62) 1.00
 30–< 35 years 15 2 1 2 7 5.55 (0.47–65.04) 0.189
 > 35 years 32 4 1 2 3 2.77 (0.24–31.81) 0.573
 Unknown 6 1 0 0 0 N/A  
Signs and symptoms
 Dysphagia
  Yes 695 94 44 92 69 0.744 (0.256–2.16) 0.809
  No 48 6 4 4 8 Ref  
 Swollen L&N
  Yes 686 92 47 98 69 4.339 (0.59–32.01) 0.195
  No 61 8 1 1 2 Ref  
 Difficulty of Breathing
  Yes 290 39 32 67 11 3.403 (1.83–6.32)  < 0.001
  No 455 61 16 33 7 Ref  
Vaccination status
 0 dose (Unvaccinated) 397 53 30 63 8 Ref  
 1 dose 28 4 3 6 11 1.58 (0.45–5.56) 0.185
 2 doses 8 1 0 0 0 N/A  
 3 doses 8 1 0 0 0 N/A  
 > 3 doses 2 0 0 0 0 N/A  
 Unknown 304 41 15 31 5 0.68 (0.36–1.30) 0.32