Fig. 2From: Performance and utility of more highly sensitive malaria rapid diagnostic testsPerformance of the HS-RDT against HRP2 concentration in PCR-confirmed specimens. Panels A and B show the sensitivity of the HS-RDT and co-RDT in samples grouped by different levels of HRP2 for a high-transmission setting (Uganda, A) and a low-transmission setting (Myanmar, B). Sensitivity is defined as the proportion of PCR-positive samples that are also detected by each RDT. The vertical lines on each bar are 95% binomial confidence intervals for each estimate. Panel C shows the probability of HS-RDT (red lines) and co-RDT (blue lines) positivity as a function of HRP2 concentration and panel D shows the probability of HS-RDT (red lines) and co-RDT (blue lines) as a function of parasite density by quantitative PCR. The shaded region indicates the 95% credible interval of the model fitBack to article page